MA5-15921 targets G6PD in FACS, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15921 immunogen is purified recombinant fragment of human G6PD expressed in E. Coli. .
MA5-15921 detects G6PD which has a predicted molecular weight of approximately 59kDa.
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: G6PD; G6PD1, glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase, G6PD
Gene Aliases: G6PD; G6PD1
UniProt ID: (Human) P11413
Entrez Gene ID: (Human) 2539