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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 330 of Human GABA A Receptor alpha 2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28222 targets GABA A Receptor alpha 2 in WB applications and shows reactivity with Human samples.
The PA5-28222 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 330 of Human GABA A Receptor alpha 2.
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alpha 2; GABA(A) receptor subunit alpha-2; GABA(A) receptor, alpha 2; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid A receptor alpha 2; Gamma-aminobutyric acid receptor subunit alpha-2