Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 5
GABRA5 Antibody (MA5-34653) in ICC/IF
Immunofluorescent analysis of GABA A Receptor alpha 5 in SH-SY-5Y cells (green). Samples were fixed in paraformaldehyde and permeabilised with 0.25% Triton X100/PBS, incubated with GABA A Receptor alpha 5 monoclonal antibody (Product # MA5-34653), followed by DAPI (blue).
Product Details
MA5-34653
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JB34-19
Immunogen
Recombinant protein within Human GABA A Receptor alpha 5 aa 1-240
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
RRID
AB_2848561
Product Specific Information
Positive Control: 293T, A549, SH-SY-5Y, rat brain tissue, mouse brain tissue.
Target Information
GABRA5 is a part of GABA, a major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GABA(A) receptor subunit alpha-5; GABAAR subunit alpha-5; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 5; Gamma-aminobutyric acid receptor subunit alpha-5
Gene Aliases: GABRA5
UniProt ID: (Human) P31644
Entrez Gene ID: (Human) 2558
behavioral fear response
positive regulation of defense response to virus by host
transport
signal transduction
gamma-aminobutyric acid signaling pathway
chemical synaptic transmission
brain development
sensory perception of sound
associative learning
ion transmembrane transport
negative regulation of neuron apoptotic process
inner ear receptor cell development
innervation
cochlea development
mitophagy in response to mitochondrial depolarization
xenophagy
chloride transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support