Invitrogen

GABRE Monoclonal Antibody (S413-67)

Product Image Gallery

GABRE Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of GABRE in human neuroblastoma cell line (SK-N-BE). Sample was fixed with 4% formaldehyde (15 min at RT), incubated with GABRE monoclonal antibody (Product # MA5-27696) using a dilution of 1:100 (1 hour at RT), and followed by Goat Anti-Mouse 488, Phalloidin Texas Red and DAPI secondary antibody at a dilution of 1:100, 1:1000 (60 min at RT) and 1:5000 (5 min at RT). Images are shown as follows: (A) DAPI (blue) nuclear stain, B) Phalloidin Texas Red F-Actin stain, C) GABA-A Receptor Epsilon Antibody, D) Merged image. Magnification: 60x.

GABRE Antibody in Western Blot (WB) — Western blot analysis of GABRE in rat brain with 10 µg of sample. The sample was incubated with GABRE monoclonal antibody (Product # MA5-27696) using a dilution of 1:1000 (1 hour at RT), followed by Goat Anti-Mouse HRP (1 hour at RT) at a dilution of 1:200 and ECL development (6 min at RT). Samples were arranged as follows: Lane 1: MW Ladder, Lane 2: Rat Brain.

Product Details

MA5-27696

Applications	Tested Dilution	Publications
Western Blot (WB)	1:1,000	-
Immunohistochemistry (PFA fixed) (IHC (PFA))	1:100	-
Immunocytochemistry (ICC/IF)	Assay-Dependent	-

Product Specifications
Species Reactivity	Human, Rat
Host/Isotype	Mouse / IgG2A
Class	Monoclonal
Type	Antibody
Clone	S413-67
Immunogen	Fusion protein amino acids 27-253 (Extracellular N-terminus) of human GABA A Receptor Epsilon View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Protein G
Storage buffer	PBS, pH 7.4, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C
RRID	AB_2735197

Target Information

The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: GABA(A) mu Receptor; GABA(A) receptor subunit epsilon; GABA(A) receptor, epsilon; gamma-aminobutyric acid; gamma-aminobutyric acid A receptor, epsilon; gamma-aminobutyric acid (GABA) A receptor, epsilon; gamma-aminobutyric acid (GABA-A) receptor, subunit epsilon; gamma-aminobutyric acid A receptor, epsilon; Gamma-aminobutyric acid receptor subunit epsilon

Gene Aliases: GABRE

UniProt ID: (Human) P78334

Entrez Gene ID: (Human) 2564, (Rat) 65191

Molecular Function: ligand-gated ion channel