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MA5-15637 targets GATA1 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15637 immunogen is purified recombinant fragment of human GATA1 expressed in E. Coli.
MA5-15637 detects GATA1 which has a predicted molecular weight of approximately 42.7kDa.
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Eryf1; Erythroid transcription factor; erythroid transcription factor 1; GATA binding protein 1 (globin transcription factor 1); GATA-1; GATA-binding factor 1; globin transcription factor 1; HGNC:4170; NF-E1 DNA-binding protein; nuclear factor, erythroid 1; transcription factor GATA1
Gene Aliases: ERYF1; GATA-1; GATA1; GF-1; GF1; NF-E1; NFE1; XLANP; XLTDA; XLTT
UniProt ID: (Human) P15976
Entrez Gene ID: (Human) 2623
Molecular Function: DNA-binding transcription factor