Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1-5 µg/mL | - |
Immunocytochemistry (ICC/IF) |
10 µg/mL | - |
ELISA (ELISA) |
0.1 ng/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2b, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1A5 |
Immunogen |
GATA2 (AAH18988, 1 a.a. approximately 102 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
See Label |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4 |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Sequence of this protein is as follows: MEVAPEQPRW MAHPAVLNAQ HPDSHHPGLA HNYMEPAQLL PPDEVDVFFN HLDSQGNPYY ANPAHARARV SYSPAHARLT GGQMCRPHLL HSPGLPWLDG GK
GATA2 (GATA binding protein 2) belongs to the GATA family of transcription factors. GATA proteins play a very important role in signaling pathways controlling proliferation and differentiation of erythroid progenitor cells. There are 6 transcription factors in the GATA family: GATA1 to GATA6. GATA2 is a transcriptional activator regulating endothelin-1 gene expression in endothelial cells. It also appears to be involved in differentiation of other tissue types (uro-genital and nervous) during embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endothelial transcription factor GATA-2; FLJ45948; GATA-binding protein 2; MGC2306
Gene Aliases: DCML; GATA2; IMD21; MONOMAC; NFE1B
UniProt ID: (Human) P23769
Entrez Gene ID: (Human) 2624
Molecular Function:
DNA-binding transcription factor
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