Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:4,000 | - |
Immunocytochemistry (ICC/IF) |
1:400 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
2B5A1 |
Immunogen |
GATA2 Fusion Protein Ag1557 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2300 µg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Aliquoting is unnecessary for -20°C storage.
GATA2 (GATA binding protein 2) belongs to the GATA family of transcription factors. GATA proteins play a very important role in signaling pathways controlling proliferation and differentiation of erythroid progenitor cells. There are 6 transcription factors in the GATA family: GATA1 to GATA6. GATA2 is a transcriptional activator regulating endothelin-1 gene expression in endothelial cells. It also appears to be involved in differentiation of other tissue types (uro-genital and nervous) during embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endothelial transcription factor GATA-2; FLJ45948; GATA-binding protein 2; MGC2306
Gene Aliases: DCML; Gata-2; GATA2; IMD21; MONOMAC; NFE1B
UniProt ID: (Human) P23769, (Mouse) O09100
Entrez Gene ID: (Human) 2624, (Mouse) 14461
Molecular Function:
DNA-binding transcription factor
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