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|Tested species reactivity||Human, Rat|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||Recombinant protein encoding the excreted domain of human GCDFP15|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:30-1:60|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-11633 targets GCDFP-15 in IHC (P) applications and shows reactivity with Human and Rat samples.
The MA5-11633 immunogen is recombinant protein encoding the excreted domain of human GCDFP15.
Gross cystic disease of the breast is benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is composed of several glycoproteins including a unique 15kDa monomer protein, Gross Cystic Disease Fluid Protein-15 (GCDFP15). Cytosolic analysis of normal tissue specimens from all major organs has demonstrated GCDFP15 in apocrine epithelia, lacrimal, ceruminous and Moll's glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. GCDFP15 and prostate specific antigen are co-expressed in androgen receptor-positive breast tumours.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Morphological features and mucin expression profile of breast carcinomas with signet-ring cell differentiation.
MA5-11633 was used in immunohistochemistry - paraffin section to characterize the morphological features and mucin expression profile of breast carcinomas with signet-ring cell differentiation.
|Bartosch C,Mendes N,Rios E,Rodrigues M,Eloy C,Reis CA,Amendoeira I||Pathology, research and practice (211:588)||2015|
A systematic analysis of commonly used antibodies in cancer diagnostics.
MA5-11633 was used in immunohistochemistry to perform a systematic study of the diagnostic power of a range of antibodies commonly used in the diagnosis of cancer
|Gremel G,Bergman J,Djureinovic D,Edqvist PH,Maindad V,Bharambe BM,Khan WA,Navani S,Elebro J,Jirström K,Hellberg D,Uhlén M,Micke P,Pontén F||Histopathology (64:293)||2014|
Immunohistochemistry in the differential diagnostics of primary lung cancer: an investigation within the Southern Swedish Lung Cancer Study.
MA5-11633 was used in immunohistochemistry to study the diagnostic value of a range of immunohistochemical markers in distinguishing different types of primary lung cancer
|Brunnström H,Johansson L,Jirström K,Jönsson M,Jönsson P,Planck M||American journal of clinical pathology (140:37)||2013|
Amplification of the prolactin receptor gene in mammary lobular neoplasia.
MA5-11633 was used in immunohistochemistry to study amplification of the prolactin receptor gene in mammary neoplasia.
|Tran-Thanh D,Arneson NC,Pintilie M,Deliallisi A,Warren KS,Bane A,Done SJ||Breast cancer research and treatment (128:31)||2011|
Sclerosing polycystic adenosis of the parotid gland: report of a bifocal, paucicystic variant with ductal carcinoma in situ and pronounced stromal distortion mimicking invasive carcinoma.
MA5-11633 was used in immunohistochemistry to report a rare clinical case of sclerosing polycystic adenosis of the parotid gland
|Petersson F,Tan PH,Hwang JS||Head and neck pathology (5:188)||2011|
Metastasis to the breast from an adenocarcinoma of the lung with extensive micropapillary component: a case report and review of the literature.
MA5-11633 was used in immunohistochemistry to report on a case of metastasis to the breast from an adenocarcinoma of the lung
|Maounis N,Chorti M,Legaki S,Ellina E,Emmanouilidou A,Demonakou M,Tsiafaki X||Diagnostic pathology (5:null)||2011|
The role of immunohistochemistry in discriminating primary from secondary extramammary Paget disease.
MA5-11633 was used in immunohistochemistry to investigate the usefulness of immunohistochemistry for extramammary Paget disease discrimination
|Perrotto J,Abbott JJ,Ceilley RI,Ahmed I||The American Journal of dermatopathology (32:137)||2010|
Clinocopathologic and immunohistochemical findings of multiple genital leiomyomas and mammary adenocarcinomas in a bitch.
MA5-11633 was used in immunohistochemistry to examine a case of canine multiple genital leiomyomas and mammary adenocarcinomas
|Ozmen O,Haligur M,Kocamuftuoglu M||Reproduction in domestic animals = Zuchthygiene (43:377)||2008|
Apocrine carcinomas of the breast in Turkish women: hormone receptors, c-erbB-2 and p53 immunoexpression.
MA5-11633 was used in immunohistochemistry to perform immunohistochemical studies of apocrine carcinomas in Turkish women with breast cancer
|Kaya H,Bozkurt SU,Erbarut I,Djamgoz MB||Pathology, research and practice (204:367)||2008|
An unusual apocrine carcinoma on the forehead.
MA5-11633 was used in immunohistochemistry to report on a case of unusual apocrine carcinoma of the forehead
|Misago N,Ohkawa T,Narisawa Y||The American Journal of dermatopathology (29:404)||2007|
Clear cell papulosis of the skin: a case report from Singapore.
MA5-11633 was used in immunohistochemistry to report on a case of clear cell papulosis of the skin
|Kumarasinghe SP,Chin GY,Kumarasinghe MP||Archives of pathology & laboratory medicine (128:e149)||2004|
gross cystic disease fluid protein 15; prolactin-induced protein; prolactin-inducible protein; prolactin-inducible protein homolog; SABP; secretory actin-binding protein
GCDFP-15; GCDFP15; GPIP4; PIP