Invitrogen

GDF15 Monoclonal Antibody (CL0328)

Product Image Gallery

GDF15 Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of GDF15 in human prostate using a GDF15 monoclonal antibody (Product # MA5-31346). The analysis shows moderate positivity in a subset of glandular epithelium cells.

GDF15 Antibody in Western Blot (WB) — Western blot analysis of MEF2C by a MEF2C monoclonal antibody (Product # MA5-31351). Lane 1: Marker [kDa] Lane 2: Negative control (vector only transfected HEK293T lysate) Lane 3: MEF2C Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY419349).

Product Details

Tested Applications

Dilution

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

Western Blot (WB)

1 µg/mL

Product Specifications

Species Reactivity

Human

Host / Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL0328

Immunogen

Recombinant protein corresponding to Human GDF15

Conjugate

Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Immunogen sequence: LSLAEASRAS FPGPSELHSE DSRFRELRKR YEDLLTRLRA NQSWEDSNTD LVPAPAVRIL TPEVRLGSGG HLHLRISRAA LPEGLPEASR LHRALFRLSP TASRSWDVTR PLRRQLSLAR PQAPALHLRL SPPPSQSDQL

Target Information

Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: GDF-15; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC-1; MIC1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; Placental TGF-beta; Prostate differentiation factor; PTGF-beta; PTGFB

Gene Aliases: GDF-15; GDF15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB

UniProt ID: (Human) Q99988

Entrez Gene ID: (Human) 9518

Molecular Function: growth factor signaling molecule