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Product Details
66434-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4E1G1
Immunogen
GDI1 Fusion Protein Ag17511 (1-209 aa encoded by BC000317)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDEEYDVIV LGTGLTECIL SGIMSVNGKK VLHMDRNPYY GGESSSITPL EELYKRFQLL EGPPESMGRG RDWNVDLIPK FLMANGQLVK MLLYTEVTRY LDFKVVEGSF VYKGGKIYKV PSTETEALAS NLMGMFEKRR FRKFLVFVAN FDENDPKTFE GVDPQTTSMR DVYRKFDLGQ DVIDFTGHAL ALYRTDDYLD QPCLETVNRI (1-209 aa encoded by BC000317)
Target Information
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GDI-1; GDP-dissociation inhibitor 1; Guanosine diphosphate dissociation inhibitor 1; mental retardation, X-linked 48; Oligophrenin-2; Protein XAP-4; Rab GDI alpha; Rab GDIalpha; Rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor, alpha; RABGD RABGDIA; testis secretory sperm-binding protein Li 208a
Gene Aliases: 1A; GDI1; GDIA; GDIalpha; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; XAP4
UniProt ID: (Human) P31150, (Mouse) Q96CX5, (Rat) P50398
Entrez Gene ID: (Human) 2664, (Pig) 100623607, (Mouse) 14567, (Rat) 25183
signal transduction
protein transport
Rab protein signal transduction
positive regulation of GTPase activity
negative regulation of axonogenesis
regulation of small GTPase mediated signal transduction
response to calcium ion
oxidation-reduction process
negative regulation of protein targeting to membrane
regulation of catalytic activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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