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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 17 and 242 of Human GERP|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31428 targets GERP in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31428 immunogen is recombinant fragment corresponding to a region within amino acids 17 and 242 of Human GERP.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GERP; glioblastoma expressed ring finger protein; glioblastoma-expressed RING finger protein; probable E3 ubiquitin-protein ligase TRIM8; ring finger protein 27; RNF27; tripartite motif protein TRIM8; tripartite motif-containing 8; tripartite motif-containing protein 8
GERP; RNF27; TRIM8