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Abnova

GHRL Monoclonal Antibody (3C9)

View all (27) Ghrelin antibodies

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Product Details

H00051738-M03

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

ELISA (ELISA)

10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

3C9

Immunogen

GHRL (AAH25791.1, 1 a.a. approximately 117 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Product may be used with Sandwich ELISA (Recombinant protein).

Immunogen sequence: MPSPGTVCSL LLLGMLWLDL AMAGSSFLSP EHQRVQQRKE SKKPPAKLQP RALAGWLRPE DGGQAEGAED EMEVRFNAPF DVGIKLSGVQ YQQHSQALGK FLQDILWEEA KEAPADK

Target Information

GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AMCBX1; appetite-regulating hormone isoform In2c; FIP-3; FIP3; Fip3p; ghrelin 27; ghrelin 28; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin; ghrelin/obestatin preprohormone; ghrelin/obestatin prepropeptide; growth hormone-releasing peptide; IKK-gamma; In2c-preproghrelin; IP; IP1; IP2; IPD2; motilin-related peptide; NEMO; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin

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Gene Aliases: MTLRP

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UniProt ID: (Human) Q9UBU3

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Entrez Gene ID: (Human) 51738

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Function(s)
hormone activity protein binding growth hormone-releasing hormone activity protein tyrosine kinase activator activity ghrelin receptor binding
Process(es)
gastric acid secretion negative regulation of endothelial cell proliferation glucose metabolic process G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration actin polymerization or depolymerization adult feeding behavior response to hormone hormone-mediated signaling pathway dendrite development negative regulation of angiogenesis growth hormone secretion response to nutrient levels positive regulation of insulin secretion regulation of response to food positive regulation of response to food positive regulation of appetite negative regulation of interleukin-1 beta production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of growth rate positive regulation of multicellular organism growth regulation of cell proliferation negative regulation of circadian sleep/wake cycle, REM sleep negative regulation of apoptotic process cortisol secretion positive regulation of MAPK cascade response to estrogen positive regulation of growth positive regulation of circadian sleep/wake cycle, non-REM sleep decidualization negative regulation of inflammatory response cartilage development positive regulation of corticotropin secretion positive regulation of cortisol secretion response to electrical stimulus positive regulation of synapse assembly regulation of transmission of nerve impulse positive regulation of growth hormone secretion positive regulation of growth hormone receptor signaling pathway postsynaptic modulation of chemical synaptic transmission regulation of postsynapse organization positive regulation of small intestinal transit positive regulation of cold-induced thermogenesis positive regulation of bone development positive regulation of sprouting angiogenesis positive regulation of eating behavior positive regulation of adipose tissue development positive regulation of gastro-intestinal system smooth muscle contraction positive regulation of gastric mucosal blood circulation positive regulation of small intestine smooth muscle contraction regulation of gastric motility positive regulation of vascular endothelial cell proliferation positive regulation of feeding behavior
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