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|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG2b|
|Immunogen||Mouse GITR transfectant.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 ug/1 million cells|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-70089 detects GITR in mouse samples.
MA1-70089 has been successfully used in flow cytometry and immunohistochemistry (frozen sections) procedures.
The MA1-70089 immunogen is mouse GITR transfectant.
Glucocorticoid-induced tumor necrosis factor receptor family-related gene (GITR) is a member of the tumor necrosis factor receptor (TNFR) family that is expressed at low levels on unstimulated T cells, B cells, and macrophages. Upon activation, CD4+ and CD8+ T cells up-regulate GITR expression, whereas immunoregulatory T cells constitutively express high levels of GITR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AITR; GITR-D; glucocorticoid-induced TNFR-related protein; TNFRSF18; tumor necrosis factor receptor superfamily member 18
AITR; Gitr; Tnfrsf18