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|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide, conjugated to KLH, corresponding to residues 105-123 of GJB1.|
|Contains||15mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA1-25094 detects GJB1 from human, mouse, and rat samples.
MA1-25094 has been successfully used in immunohistochemistry (frozen), and Western blot procedures.
The MA1-25094 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues 105-123 of GJB1.
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Differential gene expression in normal esophagus and Barrett's esophagus.
MA1-25094 was used in immunohistochemistry to investigate the change of gene expression patterns in Barrett esophagus
|Wang J,Qin R,Ma Y,Wu H,Peters H,Tyska M,Shaheen NJ,Chen X||Journal of gastroenterology (44:897)||2009|
CMTX; CMTX1; connexin 32; connexin-32; CX32; GAP junction 28 kDa liver protein; gap junction beta-1 protein; gap junction membrane channel protein beta 1; gap junction protein, beta 1, 32kDa
CMTX; CMTX1; Cnx32; CX32; Cxn-32; GJB1