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GNAT1 Antibody (MA5-56725) in IHC (P)
Immunohistochemistry (Paraffin) analysis of GNAT1 protein using GNAT1 Recombinant Monoclonal Antibody (Product # MA5-56725) on Paraffin-embedded mouse eye. Green: GNAT1 stained by GNAT1 antibody diluted at 1:100. Red: beta Tubulin 3/ Tuj1, a Cytoskeleton marker, stained by a beta Tubulin 3/ Tuj1 antibody diluted at 1:500. Blue: Fluoroshield with DAPI. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
MA5-56725
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2126
Immunogen
Recombinant fragment of human GNAT1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
Target Information
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: g-protein; Galpha t1; guanine nucleotide binding protein (G protein), alpha transducing 1; guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; guanine nucleotide binding protein, alpha transducing 1; Guanine nucleotide-binding protein G(t) subunit alpha-1; guanine nucleotide-binding protein G(T), alpha-1 subunit; rod photoreceptor transducin alpha 1 subunit; rod transducin alpha subunit; rod-type transducin alpha subunit; Tr alpha; transducin alpha (rod); transducin alpha subunit GNAT1; Transducin alpha-1 chain; transducin, rod-specific
Gene Aliases: CSNB1G; CSNBAD3; fk56e06; GBT1; Gnat-1; GNAT1; GNATR; Ird1; Ird2; irdc; irdr; Tralpha; transducin; wu:fk56e06
UniProt ID: (Human) P11488, (Dog) Q28300, (Mouse) P20612
Entrez Gene ID: (Human) 2779, (Dog) 403613, (Mouse) 14685, (Rat) 363143, (Zebrafish) 140428
detection of chemical stimulus involved in sensory perception of bitter taste
protein folding
signal transduction
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
visual perception
phototransduction, visible light
cell proliferation
response to light stimulus
response to light intensity
rhodopsin mediated signaling pathway
regulation of rhodopsin mediated signaling pathway
eye photoreceptor cell development
detection of light stimulus involved in visual perception
sensory perception of umami taste
positive regulation of cyclic-nucleotide phosphodiesterase activity
negative regulation of cyclic-nucleotide phosphodiesterase activity
retina development in camera-type eye
cellular response to electrical stimulus
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
phototransduction
response to stimulus
metabolic process
adenosine receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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