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Product Details
PA5-103881
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:3,000 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human GNB3, corresponding to a region within C-terminal amino acids. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2853213 |
Target Information
Heterotrimeric guanine nucleotide-binding proteins in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein beta-4 subunit; G protein beta-subunit; G protein, beta-3 subunit; G-protein beta 4 subunit; gbb3; gbb4; GTP-binding regulatory protein beta-3 chain; guanine nucleotide binding protein (G protein), beta 3; guanine nucleotide binding protein (G protein), beta 4; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide binding protein (G protein), beta polypeptide 4; guanine nucleotide binding protein beta 4 subunit; guanine nucleotide binding protein, beta 3; guanine nucleotide binding protein, beta 4; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding protein subunit beta-4; guanine nucleotide-binding protein, beta-3 subunit; hypertension associated protein; Transducin beta chain 3; Transducin beta chain 4
Gene Aliases: 6720453A21Rik; CMTD1F; CSNB1H; G(beta)4; Gnb-3; GNB3; GNB4
UniProt ID: (Human) P16520, (Human) Q9HAV0, (Mouse) Q61011, (Rat) P52287, (Mouse) P29387, (Rat) O35353
Entrez Gene ID: (Human) 2784, (Human) 59345, (Mouse) 14695, (Rat) 60449, (Mouse) 14696, (Rat) 294962
Molecular Function:
heterotrimeric G-protein
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