|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide made to an internal region of the human GOLM1/GOLPH2 protein (within residues 250-400).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol, 0.1% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-23076 reacts with GOLM1 in human samples.
PA5-23076 has been successfully used in Western Blot and Immunocytochemistry/Immunofluorescence applications.
The PA5-23076 immunogen is a genomic peptide made to an internal region of the human GOLM1 protein (within residues 250-400).
In liver, prostate and lung, both viral and non-viral related disease is correlated to the upregulation of GOLPH2, also known as GOLM1, GP73 or Golgi phosphoprotein 2. While it remains unclear how viral insertions are manifested into the Golgi apparatus and subsequent shepherding of proteins, GOLPH2 seems to be affected by the insertions in such a way that it can be attributed to disease phenotypes. Furthermore, because GOLPH2 is so uniquely regulated in cells, it can be successfully used as a clinically relevant molecular biomarker for cancer. As it is secreted and excreted, GOLPH2 is a useful biomarker because of relative ease of sampling in urine and direct correlation to urine concentrations and disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.