This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: RCIPASLDAY YSSQDPNSRS RFYTVISHYS VAKQSTARAI GPWLSAAAVI HEPKPPKTQG H
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: endothelial cell LPL transporter; Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; GlycosylPhosphatidylInositol-anchored high-density lipoprotein-binding protein 1; GPI anchored high density lipoprotein binding protein 1; GPI-anchored HDL-binding protein 1; GPI-anchored HDL-binding protein 1 antibody; GPI-anchored High-Density Lipid-binding protein 1 antibody; GPI-HBP1; HDLBP; HDLBP1; High density lipoprotein-binding protein 1
Gene Aliases: GPI-HBP1; GPIHBP1; HBP1; HYPL1D
UniProt ID: (Human) Q8IV16
Entrez Gene ID: (Human) 338328