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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR109B / HM74.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||19 - 38 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
BLAST analysis of the peptide immunogen showed 100% homology with human protein HCAR2 and 50% homology with GPR81.
Percent identity with other species by BLAST analysis: Human, Gorilla, Dog, Hamster, Panda (100%) Mouse, Horse, Guinea pig (95%) Rat (90%).
This is a receptor for nicotinic acid. Its expression has been reported in adipose and spleen, as well as lymphocytes and monocytes. ESTs have been isolated from adipose, blood, liver, liver/spleen, placenta, prostate, and testis libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
G protein-coupled receptor 109B; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; GPR109B; GTP-binding protein; HCA3; HCAR3; HM74; HM74b; hydroxy-carboxylic acid receptor 3; niacin receptor 2; NIACR2; nicotinic acid receptor 2; Puma-g; PUMAG; Putative chemokine receptor
GPR109B; HCA3; HCAR3; HM74; HM74B; NIACR2; Puma-g; PUMAG