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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 15 amino acid peptide from 3rd cytoplasmic domain of human GPR6.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||6 - 9 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Rabbit, Pig (100%) Opossum (80%).
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR6 is a member of this family (subfamily lysophospholipid/lysosphingolipid). GPR6 has been reported to be expressed in brain, particularly in the putamen, and to a lesser extent, in the frontal cortex, hippocampus, and hypothalamus. An EST has been isolated from a human brain (hypothalamus) library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
G protein-coupled receptor 6; GPR6; RCNL3; sphingosine 1-phosphate receptor GPR6