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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse, Rat |
Host/Isotype |
Mouse / IgG2b |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI3E8 |
Immunogen |
Synthetic peptide |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 1% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G-protein coupled receptor 83; glucocorticoid induced receptor; Glucocorticoid-induced receptor; Hcepto9; Jp05; probable G-protein coupled receptor 83
Gene Aliases: AW045253; Gir; Gpr72; Gpr83; Jp05; RP105; RP39; RP82
UniProt ID: (Mouse) P30731, (Rat) Q8VHD7
Entrez Gene ID: (Mouse) 14608, (Rat) 140595
Molecular Function:
G-protein coupled receptor
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