|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KTGLIPENYVEFL) corresponding to the C-terminus amino acids of ARHGAP26|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia . Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARHGAP26; FLJ42530; GRAF; GTPase regulator associated with FAK; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); GTPase regulator associated with the focal adhesion kinase pp125; KIAA0621; Oligophrenin-1-like protein; OPHN1L; OPHN1L1; Rho GTPase activating protein 26; Rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26
Gene Aliases: ARHGAP26; GRAF; GRAF1; KIAA0621; OPHN1L; OPHN1L1
UniProt ID: (Human) Q9UNA1
Entrez Gene ID: (Human) 23092
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