Immunogen sequence: PVTSVEWHPQ DSGVFAASGA DHQITQWDLA VERDPEAGDV EADPGLADLP QQLLFVHQGE TELKELHWHP QCPGLLVSTA LSGFTIFRTI SV
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase.
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Protein Aliases: CUL4- and DDB1-associated WDR protein 4; glutamate rich WD repeat protein GRWD; glutamate-rich WD repeat containing 1; Glutamate-rich WD repeat-containing protein 1; regulator of ribosome biogenesis 1 homolog; WD repeat domain 28
Gene Aliases: CDW4; GRWD; GRWD1; KIAA1942; RRB1; WDR28
UniProt ID: (Human) Q9BQ67
Entrez Gene ID: (Human) 83743