MA1-7621 detects GSK3 Beta from human, rat, and Xenopus laevis samples.
MA1-7621 has been successfully used in ELISA, Western blot, immunoprecipitation and immunohistochemistry procedures.
The MA1-7621 immunogen is a purified recombinant Xenopus laevis protein.
Store at 4°C short term. For extended storage, keep at -80°C.
Menin is a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Two variants of the shorter transcript have been identified where alternative splicing affects the CDS. Five variants where alternative splicing takes place in the 5' UTR have also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 188.8.131.52; FA; Factor A; Glycogen Synthase Kinase 3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3beta isoform; intracellular kinase; Serine/threonine-protein kinase GSK3B; Xgsk-3 protein
Gene Aliases: gsk-3; gsk3; gsk3-beta; GSK3B; gsk3beta; XELAEV_180112401mg; Xgsk-3