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FIGURE: 1 / 3
GSR Antibody (MA5-53478) in ICC/IF
Immunocytochemistry analysis of GSR in HeLa cells. Nuclei were stained blue with DAPI; GSR recombinant monoclonal antibody (Product # MA5-53478) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Very low. Scale bar: 20 μm.
Product Details
MA5-53478
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB2845
Immunogen
A synthesized peptide derived from human GLUR (470-522AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis luminal protein 75; epididymis secretory sperm binding protein Li 122m; glutathione reductase; glutathione reductase 1; Glutathione reductase, mitochondrial; glutathione S-reductase; GR; GRase
Gene Aliases: AI325518; D8Ertd238e; GLUR; Gr-1; Gr1; GRD1; GSR; HEL-75; HEL-S-122m
UniProt ID: (Human) P00390, (Mouse) Q8C9Z6
Entrez Gene ID: (Human) 2936, (Mouse) 14782
glutathione-disulfide reductase activity
electron carrier activity
flavin adenine dinucleotide binding
NADP binding
oxidoreductase activity
oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
protein homodimerization activity
glutathione binding
oxidoreductase
reductase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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