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Product Details
H00009446-M03
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1B6
Immunogen
GSTO1 (NP_004823, 121 a.a. approximately 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: SKVPSLVGSF IRSQNKEDYA GLKEEFRKEF TKLEEVLTNK KTTFFGGNSI SMIDYLIWPW FERLEAMKLN ECVDHTPKLK LWMAAMKED
Target Information
The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 21; Glutathione S-transferase omega 1-1; Glutathione S-transferase omega-1; Glutathione-dependent dehydroascorbate reductase; glutathione-S-transferase like; GSTO 1-1; GSTO-1; MMA(V) reductase; Monomethylarsonic acid reductase; RP11-99N20.1; S-(Phenacyl)glutathione reductase; SPG-R
Gene Aliases: GSTO 1-1; GSTO1; GSTTLP28; HEL-S-21; P28; SPG-R
UniProt ID: (Human) P78417
Entrez Gene ID: (Human) 9446
glutathione metabolic process
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
L-ascorbic acid metabolic process
L-ascorbic acid biosynthetic process
methylation
xenobiotic catabolic process
oxidation-reduction process
negative regulation of ryanodine-sensitive calcium-release channel activity
positive regulation of ryanodine-sensitive calcium-release channel activity
cellular response to arsenic-containing substance
cellular oxidant detoxification
glutathione derivative biosynthetic process
Performance Guarantee
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