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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProt]
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Protein Aliases: general transcription factor 3C 4; General transcription factor 3C polypeptide 4; general transcription factor IIIC, polypeptide 4, 90kDa; TF3C-delta; TFIIIC 90 kDa subunit; Transcription factor IIIC 90 kDa subunit; Transcription factor IIIC subunit delta
Gene Aliases: GTF3C4; KAT12; TF3C-delta; TFIII90; TFIIIC290; TFIIIC90; TFIIICDELTA
UniProt ID: (Human) Q9UKN8
Entrez Gene ID: (Human) 9329