MA5-17086 targets GUCY1A3 in FACS, ICC, IHC, IF and WB applications and shows reactivity with Human samples.
The MA5-17086 immunogen is purified recombinant fragment of human GUCY1A3 (amino acids: 22-214) expressed in E. Coli.
MA5-17086 detects GUCY1A3 which has a predicted molecular weight of approximately 77.5kDa.
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GC-S-alpha-1; GCS-alpha-1; GCS-alpha-3; guanylate cyclase 1, soluble, alpha 3; Guanylate cyclase soluble subunit alpha-1; Guanylate cyclase soluble subunit alpha-3; Soluble guanylate cyclase large subunit
Gene Aliases: GC-SA3; GUC1A3; GUCA3; GUCSA3; GUCY1A1; GUCY1A3; MYMY6
UniProt ID: (Human) Q02108
Entrez Gene ID: (Human) 2982