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TNRC6A is a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAG repeat protein 26; CTD-2540M10.1; DKFZp666E117; EDIE; EMSY interactor protein; FLJ22043; Glycine-tryptophan protein of 182 kDa; GW182 autoantigen; MGC75384; Protein GW1; Trinucleotide repeat-containing gene 6A protein
Gene Aliases: CAGH26; GW1; GW182; KIAA1460; TNRC6; TNRC6A
UniProt ID: (Human) Q8NDV7
Entrez Gene ID: (Human) 27327
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