|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Red cell ghosts.|
|Storage buffer||tissue culture supernatant|
|Contains||<0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:15-1:30|
|Immunohistochemistry (Paraffin) (IHC (P))||1:15-1:30|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-27131 detects Glycophorin C from human samples.
MA1-27131 has been successfully used in immunohistochemistry (frozen/paraffin) procedures. Positive control of tonsil suggested.
The MA1-27131 immunogen is red cell ghosts.
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.