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The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. laevis, Bovine and Dog
The gamma-tubulin (TUBG1; relative molecular weight about 48 kDa) is a minor member of tubulin family (less that 0.01% of tubulin dimer). The gamma-tubulin ring structures, however, serve to provide structural primer for initiation of microtubular nucleation and growth, thereby being crutial for microtubule-based cellular processes, above all for mitotic spindle formation. In animal cells, a center of microtubule organization is the centrosome composed of a pair of cylindrical centrioles surrounded by fibrous pericentriolar material containing gamma-tubulin. Formation of the mitotic spindle is preceded by duplication of centrosome during S phase. Before mitosis, both centrosomes increase their microtubule nucleation capacity and form two microtuble asters that are pushed apart from each other by the forces of motor proteins associated at the microtubule surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: centrosome marker; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1; Tubulin gamma-1 chain; tubulin, gamma 1; tubulin, gamma polypeptide
Gene Aliases: CDCBM4; GCP-1; TUBG; TUBG1; TUBGCP1
UniProt ID: (Human) P23258
Entrez Gene ID: (Human) 7283
Molecular Function:
cytoskeletal protein
microtubule family cytoskeletal protein
tubulin
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