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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 224 of Human Gasdermin-B|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31010 targets Gasdermin-B in IF and WB applications and shows reactivity with Human samples.
The PA5-31010 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 224 of Human Gasdermin-B.
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
gasdermin-B; gasdermin-like protein; GSDML; PRO2521
GSDMB; GSDML; PP4052; PRO2521