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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues T(364) N P S V A T F S L I N G N I C H E R Y V(384) of human GRP-R receptor protein.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1 µg/ml|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA3-304 detects GRP-R/ BB2 in human samples.
PA3-304 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects a broad ~65 kDa band representing the various glycosylated forms of GRP-R.
The PA3-304 immunogen is a synthetic peptide corresponding to residues T(364) N P S V A T F S L I N G N I C H E R Y V(384) of human GRP-R receptor protein.
Gastrin-releasing peptide-preferring bombesin receptor is often detected in prostate and breast carcinomas. These are confined to the plasma membrane and uniformly present on nearly all tumor cells. These anti-peptide antibodies will facilitate identification of these tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
bombesin receptor 2; Gastrin-releasing peptide preferring bombesin receptor.; GRP-preferring bombesin receptor; GRP-R
BB2; BB2R; GRPR