|Tested species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues T(364) N P S V A T F S L I N G N I C H E R Y V(384) of human GRP-R receptor protein.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1 µg/ml|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
PA3-304 detects GRP-R/ BB2 in human samples.
PA3-304 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects a broad ~65 kDa band representing the various glycosylated forms of GRP-R.
The PA3-304 immunogen is a synthetic peptide corresponding to residues T(364) N P S V A T F S L I N G N I C H E R Y V(384) of human GRP-R receptor protein.
Gastrin-releasing peptide-preferring bombesin receptor is often detected in prostate and breast carcinomas. These are confined to the plasma membrane and uniformly present on nearly all tumor cells. These anti-peptide antibodies will facilitate identification of these tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Immunohistochemical detection of bombesin receptor subtypes GRP-R and BRS-3 in human tumors using novel antipeptide antibodies.
PA3-304 was used in immunocytochemistry, immunohistochemistry and western blot to investigate the expression of bombesin receptor 3 and gastrin-releasing peptide receptor in human tumors
|Schulz S,Röcken C,Schulz S||Virchows Archiv : an international journal of pathology (449:421)||2006|