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|Tested species reactivity||Bovine, Human, Pig, Rabbit|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified, full length, native human protein.|
|Contains||15mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24939 detects Gelsolin from human, bovine, porcine, and rabbit samples.
MA1-24939 has been successfully used in immunofluorescence, ELISA and Western blot procedures. The predicted molecular weight is 86 kDa.
The MA1-24939 immunogen is purified, full length, native human protein.
Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin which appears to account for the difference in relative molecular weights.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
actin-depolymerizing factor; ADF; brevin; gelsolin; gelsolin (amyloidosis, Finnish type); GSN
ADF; AGEL; GSN