ABS 017-20-02 detects Gelsolin from human samples.
ABS 017-20-02 has been successfully used in ELISA and western blot procedures. ABS 017-20-02 does not work as capture antibody in sandwich ELISA.
The ABS 017-20-02 immunogen is a Gelsolin protein purified from human plasma.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-depolymerizing factor; ADF; ADFBrevin; AGEL; Brevin; Gelsolin
Gene Aliases: ADF; AGEL; GSN
UniProt ID: (Human) P06396
Entrez Gene ID: (Human) 2934