Specificity: ABS 052-121-02 cross-reacts with rat ghrelin, and is predicted to react with mouse, dog and cat based on sequence homology.
Reactivity: ABS 052-121-02 binds human ghrelin in solution. ABS 052-121-02 can be used as a detection antibody in a sandwich ELISA with capture antibody ABS 050-45-02.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Appetite-regulating hormone; Appetite-regulating hormone, Growth hormone-releasing peptide, Protein M46, Motilin-related peptide, ghrelin 27; Ghrelin; ghrelin 28; ghrelin, growth hormone secretagogue receptor ligand; Ghrelin-27; Ghrelin-28; ghrelin/obestatin preprohormone; Growth hormone secretagogue; Growth hormone-releasing peptide; In2c-preproghrelin; Motilin-related peptide; MTLRP; Obestatin; Obestatin-13; Obestatin-23; prepro-appetite regulatory hormone; preproghrelin; Protein M46
Gene Aliases: GHRL; MTLRP; UNQ524/PRO1066