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|Tested species reactivity||Human, Non-human primate, Rat|
|Published species reactivity||Rat, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Fusion protein encompassing the N-terminal region of rat GluR3.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1-3 ug/ml|
|Western Blot (WB)||5 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 2 publications below|
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Rat||Not Cited||Differential trafficking of AMPA and NMDA receptors during long-term potentiation in awake adult animals.||Williams JM,Guévremont D,Mason-Parker SE,Luxmanan C,Tate WP,Abraham WC||The Journal of neuroscience : the official journal of the Society for Neuroscience (27:14171)||2007|
|Mouse||1:600||A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A.||Jensen V,Kaiser KM,Borchardt T,Adelmann G,Rozov A,Burnashev N,Brix C,Frotscher M,Andersen P,Hvalby Ø,Sakmann B,Seeburg PH,Sprengel R||The Journal of physiology (553:843)||2003|
AMPA 3; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluA3; GluR-3; GLUR-C; GLUR-K3; GLUR3; GLURC; Glutamate receptor 3; glutamate receptor C; glutamate receptor ionotropic; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA3 (alpha 3); MRX94; RP11-349N19.3
GluA3; GluR-3; GLUR-C; GLUR-K3; GLUR3; GLURC; GRIA3; MRX94