Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); EAA5; Excitatory amino acid receptor 5; GLR7; GluK3; GluR-7; GLUR7; GluR7a; Glutamate receptor 7; Glutamate receptor ionotropic, kainate 3; glutamate receptor, ionotropic, kainate 3
Gene Aliases: EAA5; GLR7; GluK3; GLUR7; GluR7a; GRIK3
UniProt ID: (Human) Q13003
Entrez Gene ID: (Human) 2899