FIGURE: 1 / 5
MA5-31744 has been tested in indirect ELISA.
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
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Protein Aliases: dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); EAA5; Excitatory amino acid receptor 5; GluK3; GluR-7; glutamate receptor; Glutamate receptor 7; Glutamate receptor ionotropic, kainate 3; glutamate receptor, ionotropic, kainate 3
Gene Aliases: EAA5; GLR7; GluK3; GLUR7; GluR7a; GRIK3
UniProt ID: (Human) Q13003
Entrez Gene ID: (Human) 2899
Molecular Function: transmembrane signal receptor