|Immunocytochemistry (ICC)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||3-5 µg/ml|
|Western Blot (WB)||0.3-1 µg/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ESEEQKRNRVRGILR) corresponding to the internal amino acids of GLUD1 / GLUD2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine and rat based on sequence homology.
This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis tissue sperm binding protein Li 18mP; GDH 1; GDH 2; GDH1; GDH2; GLUD; GLUD1; GLUD2; GLUDP1; glutamate dehydrogenase (NAD(P)+); glutamate dehydrogenase 1; Glutamate dehydrogenase 1, mitochondrial; glutamate dehydrogenase 2; Glutamate dehydrogenase 2, mitochondrial; glutamate dehydrogenase pseudogene 1; Memory-related gene 2 protein; MGC132003; MRG-2; testicular secretory protein Li 14
Gene Aliases: Ac2-281; AI118167; GDH; Gdh-X; GDH1; GDH2; GLUD; GLUD1; GLUD2; Gludeha; Gludl; GLUDP1; MRG-2
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