This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
This antibody specifically recognizes GAC but not the KGA isoform.
Predicted reactivity: Bovine (100%).
Recommended positive controls: MDA-MB-231 cells.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Sahai (1983) demonstrated phosphate-activated glutaminase (EC 220.127.116.11) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GLS; glutaminase C; Glutaminase kidney isoform, mitochondrial; Glutaminase kidney isoform, mitochondrial 65 kDa chain; Glutaminase kidney isoform, mitochondrial 68 kDa chain; glutaminase, phosphate-activated; K-glutaminase; L-glutamine amidohydrolase
Gene Aliases: AAD20; GAC; GAM; GLS; GLS1; KGA; KIAA0838
UniProt ID: (Human) O94925
Entrez Gene ID: (Human) 2744
Molecular Function: hydrolase