|Flow Cytometry (Flow)||Assay Dependent|
|Flow Cytometry (Flow)||See 24 publications below|
|Miscellaneous PubMed (MISC)||See 11 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Non-human primate , Human , Mouse , Rhesus monkey|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human Granzyme B.|
|Excitation/Emission Profile||View spectra|
|Storage buffer||PBS with 4mg/ml BSA, sucrose|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
Granzyme A and granzyme B are serine proteases that mediate apoptotic signaling in cytotoxic T lymphocytes (CTL) and in natural killer (NK) cells. Both granzyme A and granzyme B are synthesized as inactive proenzymes, and they are stored within cytolytic granules and released by effector cells during degradation. This antibody should be useful for the localization of granzyme B-containing lytic granules and for the characterization of activated CTLs or NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C11; Cathepsin G-like 1; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA-1; CTLA1; CTSGL1; cytotoxic serine protease B; Cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin 2; Fragmentin-2; granzyme 2; Granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Granzyme-2; HLP; Human lymphocyte protein; Lymphocyte protease; SECT; T-cell serine protease 1-3E
Gene Aliases: CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; GRB; GZMB; HLP; SECT
UniProt ID: (Human) P10144
Entrez Gene ID: (Human) 3002
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