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Leinco Technologies
H-2b Monoclonal Antibody (B8-24-3), Functional Grade, In Vivo GOLD™
Product Details
H8300-100MG
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
B8-24-3
Immunogen
EL4 lymphoma cells mixed with Bordetella pertussis bacteria
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.2-7.4
Contains
no preservative
Storage conditions
4°C short term, -80°C long term
Shipping conditions
Wet ice
Product Specific Information
Endotoxin Level: <1.0 EU/mg as determined by the LAL method.
Purity: ≥95% monomer by analytical SEC and >95% by SDS Page.
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acetyl-Histone H2; H2B 291A; H2B 291B; H2b 613; H2B GL105 antibody; H2B histone family, member S; h2B-143; h2B-221; H2B-clustered histone 21; H2B-clustered histone 3; H2B-clustered histone 9; H2B.1 antibody; H2B/I; H2BK12ac; H2BK15ac; H2BK5ac; H2BS14; H2BS14p; HIST1H2BB antibody; HIST1H3I; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bg; histone 1, H2bh; histone 1, H2bj; histone 1, H2bk; histone 1, H2bm; histone 2, H2be; Histone 2B; Histone H2B type 1-A; Histone H2B type 1-B; Histone H2B type 1-C/E/G; Histone H2B type 1-F/J/L; Histone H2B type 1-H; Histone H2B type 1-K; Histone H2B type 1-M; Histone H2B type 2-E; Histone H2B, testis; Histone H2B.I; MGC125414; MGC125415; MGC125416; MGC9388; RP1-193B12.10; Testis-specific histone H2B
Gene Aliases: 2610022J01Rik; AV127319; H2b-143; H2b-221; H2b-291b; H2b-613; H2b-f; H2b-j; H2b-l; H2b-n; H2bc1; H2bc11; H2bc12; H2bc13; H2bc14; H2bc15; H2bc21; H2bc3; H2bc4; H2bc6; H2bc7; H2bc8; H2bc9; H2bfs; Hist1h2ba; Hist1h2bb; Hist1h2bc; Hist1h2be; Hist1h2bf; Hist1h2bg; Hist1h2bh; Hist1h2bj; Hist1h2bk; Hist1h2bl; Hist1h2bm; Hist1h2bn; Hist2h2be; R74621; T25626; Th2b
UniProt ID: (Mouse) P70696, (Mouse) Q64475, (Mouse) Q6ZWY9, (Mouse) Q64478, (Mouse) P10853, (Mouse) Q8CGP1, (Mouse) P10854, (Mouse) Q64524
Entrez Gene ID: (Mouse) 319177, (Mouse) 319178, (Mouse) 68024, (Mouse) 319181, (Mouse) 319182, (Mouse) 319183, (Mouse) 319184, (Mouse) 319186, (Mouse) 319190
chromatin organization
nucleosome assembly
nucleosome disassembly
inflammatory response
plasminogen activation
spermatogenesis, exchange of chromosomal proteins
positive regulation of binding
cellular response to acid chemical
mononuclear cell migration
innate immune response in mucosa
antibacterial humoral response
defense response to Gram-positive bacterium
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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