Invitrogen

H-cadherin Polyclonal Antibody

View all (20) H-cadherin antibodies

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H-cadherin Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemistry analysis of H-cadherin in LOVO. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114998) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with Alexa Fluor 594 conjugated goat anti-rabbit IgG using a dilution of 1:600.

H-cadherin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of H-cadherin in human kidney tissue sections. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114998) at a dilution of 1:100. Secondary staining was applied with HRP conjugated goat anti-rabbit.

H-cadherin Antibody in Western Blot (WB) — Western blot analysis of H-cadherin in mouse heart (left lane: treated with antigen-specific peptide). Samples were incubated with polyclonal antibody (Product # PA5-114998).

Product Details

PA5-114998

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-
Immunohistochemistry (PFA fixed) (IHC (PFA))	1:50-1:200	-
Immunocytochemistry (ICC/IF)	1:100-1:500	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	A synthesized peptide derived from human CDH13(Accession P55290), corresponding to amino acid residues Q153-Q182. View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C
RRID	AB_2899634

Target Information

The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CAD13; cadherin 13, H-cadherin (heart); Cadherin-13; CD39-like 3; CD39L3; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; H-cadherin; H-cadherin (heart); Heart cadherin; heart-cadherin; NTPDase-3; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin

Gene Aliases: 4932416G01Rik; CDH13; CDHH; Cdht; P105; T-cadherin; Tcad

UniProt ID: (Human) P55290, (Mouse) Q9WTR5

Entrez Gene ID: (Human) 1012, (Mouse) 12554

Molecular Function: cadherin