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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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Protein Aliases: H2A histone family, member Z; H2A/z; H2AZ histone; Histone H2A.Z
Gene Aliases: H2A.z; H2A.Z-1; H2A/z; H2AFZ; H2AZ; H2AZ1
UniProt ID: (Human) P0C0S5
Entrez Gene ID: (Human) 3015
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