Product References
Host Restriction Factor A3G Inhibits the Replication of Enterovirus D68 by Competitively Binding the 5' Untranslated Region with PCBP1.
Journal of virology
Li Z,Yang X,Zhao Z,Liu X,Zhang W
71-5500 was used in Western Blotting to show that host restriction factor A3G might have broad-spectrum antiviral activity against multiple enteroviruses.
Wed Jan 26 00:00:00 EST 2022
The Emerging Role of E3 Ubiquitin Ligase SMURF2 in the Regulation of Transcriptional Co-Repressor KAP1 in Untransformed and Cancer Cells and Tissues.
Cancers
Shah PA,Boutros-Suleiman S,Emanuelli A,Paolini B,Levy-Cohen G,Blank M
71-5500 was used in Western Blotting to uncover SMURF2 as a novel regulator of KAP1, governing its protein expression, interactions, and functions.
Tue Mar 22 00:00:00 EDT 2022
The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth.
eLife
Yang S,Wu X,Daoutidou EI,Zhang Y,Shimell M,Chuang KH,Peterson AJ,O'Connor MB,Zheng X
71-5500 was used in Western Blot to propose that Hh-induced Nord expression fine-tunes both the range and strength of BMP signaling in the developing Drosophila wing.
Mon Jan 17 00:00:00 EST 2022
The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes.
Cell reports
Gerosa L,Mazzoleni S,Rusconi F,Longaretti A,Lewerissa E,Pelucchi S,Murru L,Giannelli SG,Broccoli V,Marcello E,Kasri NN,Battaglioli E,Passafaro M,Bassani S
71-5500 was used in Immunoprecipitation to support a model whereby PCDH19 favors maintenance of neuronal homeostasis via negative feedback regulation of IEG expression and provide a key to interpreting PCDH19-related hyperexcitability.
Tue May 24 00:00:00 EDT 2022
Coordination of metal center biogenesis in human cytochrome c oxidase.
Nature communications
Nývltová E,Dietz JV,Seravalli J,Khalimonchuk O,Barrientos A
71-5500 was used in Western Blotting to report that in human cells the CcO copper chaperones form macromolecular assemblies and cooperate with several twin CX9C proteins to control heme a biosynthesis and coordinate copper transfer sequentially to the CuA and CuB sites.
Fri Jun 24 00:00:00 EDT 2022
USP17 is required for peripheral trafficking of lysosomes.
EMBO reports
Lin J,McCann AP,Sereesongsaeng N,Burden JM,Alsa'd AA,Burden RE,Micu I,Williams R,Van Schaeybroeck S,Evergren E,Mullan P,Simpson JC,Scott CJ,Burrows JF
71-5500 was used in Western Blotting to demonstrate that USP17 can deubiquitinate p62, and we propose that USP17 can facilitate peripheral lysosome trafficking by opposing the E3 ligase RNF26 to untether lysosomes from the ER and facilitate lysosome peripheral trafficking, lysosome protease secretion, and plasma membrane repair.
Tue Apr 05 00:00:00 EDT 2022
Chemokine PF4 Inhibits EV71 and CA16 Infections at the Entry Stage.
Journal of virology
Pei Z,Wang H,Zhao Z,Chen X,Huan C,Zhang W
71-5500 was used in Western Blotting to show that platelet factor 4 is an inhibitor of enterovirus A71 and coxsackievirus A16 infections.
Wed Jun 08 00:00:00 EDT 2022
Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.
Science (New York, N.Y.)
Gwon Y,Maxwell BA,Kolaitis RM,Zhang P,Kim HJ,Taylor JP
71-5500 was used in Western Blotting to investigate if targeting of G3BP1 weakened the stress granule-specific interaction network, resulting in granule disassembly.
Fri Jun 25 00:00:00 EDT 2021
ZNF410 represses fetal globin by singular control of CHD4.
Nature genetics
Vinjamur DS,Yao Q,Cole MA,McGuckin C,Ren C,Zeng J,Hossain M,Luk K,Wolfe SA,Pinello L,Bauer DE
71-5500 was used in CUT&RUN sequencing to identify zinc-finger protein (ZNF) 410 as an fetal hemoglobin repressor.
Sat May 01 00:00:00 EDT 2021
SAMHD1 Inhibits Multiple Enteroviruses by Interfering with the Interaction between VP1 and VP2 Proteins.
Journal of virology
Zhao Z,Li Z,Huan C,Liu X,Zhang W
71-5500 was used in Western Blot to reveal a novel mechanism for the SAMHD1 anti-EV replication activity.
Thu Jun 10 00:00:00 EDT 2021
Development and characterisation of SMURF2-targeting modifiers.
Journal of enzyme inhibition and medicinal chemistry
Manikoth Ayyathan D,Levy-Cohen G,Shubely M,Boutros-Suleiman S,Lepechkin-Zilbermintz V,Shokhen M,Albeck A,Gruzman A,Blank M
71-5500 was used in Western Blotting to generate and investigate a set of SMURF2-targeting synthetic peptides and peptidomimetics designed to stimulate SMURF2's autoubiquitination and turnover via a disruption of the inhibitory intramolecular interaction between its C2 and HECT domains.
Wed Dec 01 00:00:00 EST 2021
Precise levels of the Drosophila adaptor protein Dreadlocks maintain the size and stability of germline ring canals.
Journal of cell science
Stark K,Crowe O,Lewellyn L
71-5500 was used in Immunohistochemistry to describe a novel role for the conserved SH2/SH3 adaptor protein Dreadlocks in regulation of the germline ring canals in the developing Drosophila egg chamber.
Thu Apr 15 00:00:00 EDT 2021
Bombyx mori Nucleopolyhedrovirus (BmNPV) Induces G2/M Arrest to Promote Viral Multiplication by Depleting BmCDK1.
Insects
Xiao Q,Dong ZQ,Zhu Y,Zhang Q,Yang X,Xiao M,Chen P,Lu C,Pan MH
71-5500 was used in Immunohistochemistry-immunofluorescence to find that BmNPV induced G2/M arrest to support its replication and proliferation by reducing the expression of BmCDK1 and BmCyclin B. Co-immunoprecipitation assays confirmed that BmNPV IAP1 interacted with BmCDK1.
Wed Dec 08 00:00:00 EST 2021
SMURF2-mediated ubiquitin signaling plays an essential role in the regulation of PARP1 PARylating activity, molecular interactions, and functions in mammalian cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ilić N,Tao Y,Boutros-Suleiman S,Kadali VN,Emanuelli A,Levy-Cohen G,Blank M
71-5500 was used in Western Blotting to suggest that SMURF2-mediated ubiquitin signaling plays an essential role in PARP1 regulation, beyond the regulation of its protein expression.
Thu Apr 01 00:00:00 EDT 2021
TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47.
Cell reports
Urbina FL,Menon S,Goldfarb D,Edwards R,Ben Major M,Brennwald P,Gupton SL
71-5500 was used in Western Blot to find the E3 ubiquitin ligase TRIM67 promotes FVF-like exocytosis in part by limiting incorporation of the Qb/Qc SNARE SNAP47 into SNARE complexes and, thus, SNAP47 involvement in exocytosis.
Tue Feb 09 00:00:00 EST 2021
Snapin Specifically Up-Regulates Cav1.3 Ca2+ Channel Variant with a Long Carboxyl Terminus.
International journal of molecular sciences
Jeong S,Rhee JS,Lee JH
71-5500 was used in ELISA, Immunocytochemistry to isolate Snapin2 as a molecular partner interacting with the long carboxyl terminus of the rat Cav1.3L Ca2+ channel variant.
Tue Oct 19 00:00:00 EDT 2021
Snapin Specifically Up-Regulates Cav1.3 Ca2+ Channel Variant with a Long Carboxyl Terminus.
International journal of molecular sciences
Jeong S,Rhee JS,Lee JH
71-5500 was used in ELISA, Immunocytochemistry to isolate Snapin2 as a molecular partner interacting with the long carboxyl terminus of the rat Cav1.3L Ca2+ channel variant.
Tue Oct 19 00:00:00 EDT 2021
Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24.
Nature communications
Cao X,Khitun A,Luo Y,Na Z,Phoodokmai T,Sappakhaw K,Olatunji E,Uttamapinant C,Slavoff SA
71-5500 was used in Western Blotting to implicate alt-RPL36 as an upstream regulator of PI3K-AKT-mTOR signaling.
Thu Jan 21 00:00:00 EST 2021
UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy.
Nature communications
Yoon MJ,Choi B,Kim EJ,Ohk J,Yang C,Choi YG,Lee J,Kang C,Song HK,Kim YK,Woo JS,Cho Y,Choi EJ,Jung H,Kim C
71-5500 was used in Immunoprecipitation to propose that UXT may serve as a potential therapeutic target for drugs aimed at treating neurodegenerative diseases associated with protein aggregation, including ALS.
Mon Mar 29 00:00:00 EDT 2021
TACAN Is an Ion Channel Involved in Sensing Mechanical Pain.
Cell
Beaulieu-Laroche L,Christin M,Donoghue A,Agosti F,Yousefpour N,Petitjean H,Davidova A,Stanton C,Khan U,Dietz C,Faure E,Fatima T,MacPherson A,Mouchbahani-Constance S,Bisson DG,Haglund L,Ouellet JA,Stone LS,Samson J,Smith MJ,Ask K,Ribeiro-da-Silva A,Blunck R,Poole K,Bourinet E,Sharif-Naeini R
71-5500 was used in Western Blotting to report identification of TACAN (Tmem120A), an ion channel involved in sensing mechanical pain. TACAN is expressed in a subset of nociceptors, and its heterologous expression increases mechanically evoked currents in cell lines.
Thu Mar 05 00:00:00 EST 2020
Mutated CEACAMs Disrupt Transforming Growth Factor Beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis.
Gastroenterology
Gu S,Zaidi S,Hassan MI,Mohammad T,Malta TM,Noushmehr H,Nguyen B,Crandall KA,Srivastav J,Obias V,Lin P,Nguyen BN,Yao M,Yao R,King CH,Mazumder R,Mishra B,Rao S,Mishra L
71-5500 was used in Western Blotting to study interactions among proteins of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family, which interact with microbes, and transforming growth factor beta (TGFB) signaling pathway, which is often altered in colorectal cancer cells. We investigated mechanisms by which CEACAM proteins inhibit TGFB signaling and alter the intestinal microbiome to promote colorectal carcinogenesis.
Wed Jan 01 00:00:00 EST 2020
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein.
Nature cell biology
Zhang R,Lee DM,Jimah JR,Gerassimov N,Yang C,Kim S,Luvsanjav D,Winkelman J,Mettlen M,Abrams ME,Kalia R,Keene P,Pandey P,Ravaux B,Kim JH,Ditlev JA,Zhang G,Rosen MK,Frost A,Alto NM,Gardel M,Schmid SL,Svitkina TM,Hinshaw JE,Chen EH
71-5500 was used in Western Blotting to reveal a function of dynamin in propelling invasive membrane protrusions during myoblast fusion in vivo.
Mon Jun 01 00:00:00 EDT 2020
ATP1B3 cooperates with BST-2 to promote hepatitis B virus restriction.
Journal of medical virology
Zheng B,Zhang J,Zheng T,Wang H,Li Z,Huan C,Ning S,Wang Y,Zhang W
71-5500 was used in Western Blotting to identify ATP1B3 as a novel candidate of HBV restrictor with unrevealed mechanism.
Sat Feb 01 00:00:00 EST 2020
Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required for Toxoplasma apical complex biogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Back PS,O'Shaughnessy WJ,Moon AS,Dewangan PS,Hu X,Sha J,Wohlschlegel JA,Bradley PJ,Reese ML
71-5500 was used in Immunocytochemistry-immunoflourescence to show AC9 regulates ERK7 by scaffolding it at its site of action while maintaining it in an "off" state until the specific binding of a true substrate.
Tue Jun 02 00:00:00 EDT 2020
A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance.
The Journal of cell biology
Boyer NP,McCormick LE,Menon S,Urbina FL,Gupton SL
71-5500 was used in Western Blotting to show that the TRIM9-related protein TRIM67 outcompetes TRIM9 for interacting with VASP and antagonizes TRIM9-dependent VASP ubiquitination.
Mon Jan 06 00:00:00 EST 2020
GBP5 Is an Interferon-Induced Inhibitor of Respiratory Syncytial Virus.
Journal of virology
Li Z,Qu X,Liu X,Huan C,Wang H,Zhao Z,Yang X,Hua S,Zhang W
71-5500 was used in Western Blotting to provide information for the understanding of the pathogenic mechanisms of RSV and host immunity as well as the complicated interplay between the virus and host.
Wed Oct 14 00:00:00 EDT 2020
Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome.
Frontiers in cell and developmental biology
Gella A,Prada-Dacasa P,Carrascal M,Urpi A,González-Torres M,Abian J,Sanz E,Quintana A
71-5500 was used in Western Blot, Immunohistochemistry to show a marked reduction of complex I N-module subunit abundance and an increase in the levels of the assembly factor NDUFA2.
Mon Sep 28 00:00:00 EDT 2020
Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome.
Frontiers in cell and developmental biology
Gella A,Prada-Dacasa P,Carrascal M,Urpi A,González-Torres M,Abian J,Sanz E,Quintana A
71-5500 was used in Western Blot, Immunohistochemistry to show a marked reduction of complex I N-module subunit abundance and an increase in the levels of the assembly factor NDUFA2.
Mon Sep 28 00:00:00 EDT 2020
A Family of Auxiliary Subunits of the TRP Cation Channel Encoded by the Complex inaF Locus.
Genetics
Chen Z,Montell C
71-5500 was used in Western Blotting to reveal a previously unknown TRP interacting protein, INAF-C, which is expressed exclusively in the ultraviolet-sensing R7 photoreceptor cells, using Drosophila melanogaster.
Wed Jul 01 00:00:00 EDT 2020
ERK Regulates NeuroD1-mediated Neurite Outgrowth via Proteasomal Degradation.
Experimental neurobiology
Lee TY,Cho IS,Bashyal N,Naya FJ,Tsai MJ,Yoon JS,Choi JM,Park CH,Kim SS,Suh-Kim H
71-5500 was used in Western Blotting to provide evidence to indicate that a longer protein half-life enhanced the overall activity of NeuroD1 in stimulating downstream genes and neuronal differentiation.
Tue Jun 30 00:00:00 EDT 2020
S1 Domain RNA-Binding Protein CvfD Is a New Posttranscriptional Regulator That Mediates Cold Sensitivity, Phosphate Transport, and Virulence in Streptococcus pneumoniae D39.
Journal of bacteriology
Sinha D,Zheng JJ,Tsui HT,Richardson JD,De Lay NR,Winkler ME
71-5500 was used in Western Blotting to show that the S1 domain protein CvfD exerts a broad impact on pneumococcal physiology and virulence, partly by post-transcriptional gene regulation.
Tue Aug 25 00:00:00 EDT 2020
An Endoplasmic Reticulum CREC Family Protein Regulates the Egress Proteolytic Cascade in Malaria Parasites.
mBio
Fierro MA,Asady B,Brooks CF,Cobb DW,Villegas A,Moreno SNJ,Muralidharan V
71-5500 was used in Western Blot to generate conditional mutants of the Plasmodium falciparum endoplasmic reticulum-resident calcium-binding protein (PfERC).
Tue Feb 25 00:00:00 EST 2020
Proteolytic Restriction of Chordin Range Underlies BMP Gradient Formation.
Cell reports
Tuazon FB,Wang X,Andrade JL,Umulis D,Mullins MC
71-5500 was used in Immunocytochemistry to determine that the proteases Bmp1a and Tolloid spatially restrict the BMP antagonist Chordin in dorsoventral (DV) axial patterning of the early zebrafish gastrula, combining rigorous mutant analyses with quantitative immunofluorescence.
Tue Aug 18 00:00:00 EDT 2020
SERINC5 Inhibits the Secretion of Complete and Genome-Free Hepatitis B Virions Through Interfering With the Glycosylation of the HBV Envelope.
Frontiers in microbiology
Liu Y,Wang H,Zhang J,Yang J,Bai L,Zheng B,Zheng T,Wang Y,Li J,Zhang W
71-5500 was used in Western Blotting to demonstrate that SERINC5 potently inhibited HBV virion secretion in the supernatant without affecting intracellular core particle-associated DNA and the total RNA, but SERINC3 and SERINC1 did not.
Mon Sep 28 00:00:00 EDT 2020
Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism.
Nature communications
Li J,Xie Y,Cornelius S,Jiang X,Sando R,Kordon SP,Pan M,Leon K,Südhof TC,Zhao M,Araç D
71-5500 was used in Flow cytometry/Cell sorting to investigate the regulatory mechanisms governing alternative splicing of teneurins with latrophilins.
Fri May 01 00:00:00 EDT 2020
Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.
eLife
Díaz-Alonso J,Morishita W,Incontro S,Simms J,Holtzman J,Gill M,Mucke L,Malenka RC,Nicoll RA
71-5500 was used in Western Blotting to support a model in which LTP generates synaptic slots, which capture passively diffusing AMPARs.
Mon Aug 24 00:00:00 EDT 2020
Triciribine Engages ZFP36L1 and HuR to Stabilize LDLR mRNA.
Molecules (Basel, Switzerland)
Sundvold H
71-5500 was used in Immunocytochemistry-immunoflourescence to suggest that TCN utilizes ERK signaling to increase the activity of HuR and inhibit ZFP36L1 to stabilize LDLR mRNA in HepG2 cells.
Thu Oct 01 00:00:00 EDT 2020
Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.
Nature communications
Dufey E,Bravo-San Pedro JM,Eggers C,González-Quiroz M,Urra H,Sagredo AI,Sepulveda D,Pihán P,Carreras-Sureda A,Hazari Y,Sagredo EA,Gutierrez D,Valls C,Papaioannou A,Acosta-Alvear D,Campos G,Domingos PM,Pedeux R,Chevet E,Alvarez A,Godoy P,Walter P,Glavic A,Kroemer G,Hetz C
71-5500 was used in Immunocytochemistry-immunoflourescence to identify the selective activation of the unfolded protein response transducer IRE1α under genotoxic stress to modulate repair programs and sustain cell survival.
Thu May 14 00:00:00 EDT 2020
Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5.
Cell reports
Cui S,Yu Q,Chu L,Cui Y,Ding M,Wang Q,Wang H,Chen Y,Liu X,Wang C
71-5500 was used in Western Blot, Immunoprecipitation to report that nuclear cGAS is indispensable for inducing cytokines and chemokines triggered by RNA/DNA viruses.
Tue Dec 08 00:00:00 EST 2020
Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5.
Cell reports
Cui S,Yu Q,Chu L,Cui Y,Ding M,Wang Q,Wang H,Chen Y,Liu X,Wang C
71-5500 was used in Western Blot, Immunoprecipitation to report that nuclear cGAS is indispensable for inducing cytokines and chemokines triggered by RNA/DNA viruses.
Tue Dec 08 00:00:00 EST 2020
Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish.
eLife
Allen RS,Tajer B,Shore EM,Mullins MC
71-5500 was used in Immunohistochemistry-immunofluorescence to investigate the mechanism by which FOP-ACVR1 enhances pSmad1/5 activation (leading to Fibrodysplasia ossificans progressiva (FOP)), using zebrafish embryonic dorsoventral (DV) patterning assays.
Tue Sep 08 00:00:00 EDT 2020
NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly.
Cell reports
Kweon HJ,Gu S,Witham E,Dhara M,Yu H,Mandon ED,Jawhari A,Bredt DS
71-5500 was used in Immunocytochemistry to identify ER pathways that mediate α7 assembly by NACHO and provide insights into novel pharmacological strategies for these crucial nicotinic receptors.
Tue Aug 11 00:00:00 EDT 2020
Coxsackievirus A6 Induces Necroptosis for Viral Production.
Frontiers in microbiology
Zhang S,Yu X,Meng X,Huo W,Su Y,Liu J,Liu Y,Zhang J,Wang S,Yu J
71-5500 was used in Western Blot to investigate the pathogenic mechanism of Caxsackievirus A6.
Mon Sep 28 00:00:00 EDT 2020
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Nature cell biology
Carreras-Sureda A,Jaña F,Urra H,Durand S,Mortenson DE,Sagredo A,Bustos G,Hazari Y,Ramos-Fernández E,Sassano ML,Pihán P,van Vliet AR,González-Quiroz M,Torres AK,Tapia-Rojas C,Kerkhofs M,Vicente R,Kaufman RJ,Inestrosa NC,Gonzalez-Billault C,Wiseman RL,Agostinis P,Bultynck G,Court FA,Kroemer G,Cárdenas JC,Hetz C
71-5500 was used in Western Blotting to demonstrate the alternative function of the endoplasmic reticulum stress transducer IRE1α in orchestrating the communication between the endoplasmic reticulum and mitochondria to sustain bioenergetics by acting as the structural determinant which controls mitochondrial calcium uptake of mitochondria-associated membranes (MAMs).
Sat Jun 01 00:00:00 EDT 2019
The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads.
Molecular cell
Lu F,Portz B,Gilmour DS
71-5500 was used in Immunohistochemistry to show that a truncated C-terminal domain composed solely of YSPTSPS repeats supports Drosophila viability but that a C-terminal domain with enough YSPTSPS repeats to match the length of the wild-type Drosophila C-terminal domain is defective.
Thu Mar 21 00:00:00 EDT 2019
A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1.
Protein & cell
Xu Y,Ji K,Wu M,Hao B,Yao KT,Xu Y
71-5500 was used in Western Blotting to determine the role of HERC4 in mammary tumourigenesis.
Thu Aug 01 00:00:00 EDT 2019
Identification of NMS-873, an allosteric and specific p97 inhibitor, as a broad antiviral against both influenza A and B viruses.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Zhang J,Hu Y,Hau R,Musharrafieh R,Ma C,Zhou X,Chen Y,Wang J
71-5500 was used in Immunoprecipitation to demonstrate that p97 could be a novel antiviral target and its inhibitor, NMS-873, is a promising antiviral drug candidate.
Wed May 15 00:00:00 EDT 2019
A Ubiquitous Platform for Bacterial Nanotube Biogenesis.
Cell reports
Bhattacharya S,Baidya AK,Pal RR,Mamou G,Gatt YE,Margalit H,Rosenshine I,Ben-Yehuda S
71-5500 was used in Immunocytochemistry-immunoflourescence to demonstrate that the CORE-derived nanotube is a ubiquitous organelle that facilitates intercellular molecular trade across the bacterial kingdom.
Tue Apr 09 00:00:00 EDT 2019
Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection.
mBio
Scholte FEM,Hua BL,Spengler JR,Dzimianski JV,Coleman-McCray JD,Welch SR,McMullan LK,Nichol ST,Pegan SD,Spiropoulou CF,Bergeron É
71-5500 was used in Western Blotting to demonstrate that artificially prolonged binding of the ovarian tumour (OTU) to a substrate inhibits virus infection, which provides novel insights into CCHFV OTU function during the viral replicative cycle and highlights the OTU as a potential antiviral target.
Tue Jul 23 00:00:00 EDT 2019
RiboTag: Ribosomal Tagging Strategy to Analyze Cell-Type-Specific mRNA Expression In Vivo.
Current protocols in neuroscience
Sanz E,Bean JC,Carey DP,Quintana A,McKnight GS
71-5500 was used in Immunohistochemistry to discuss the technical procedures and describe important considerations relevant to the analysis of the data.
Sat Jun 01 00:00:00 EDT 2019
The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis.
Scientific reports
Tu J,Park S,Yu W,Zhang S,Wu L,Carmon K,Liu QJ
71-5500 was used in Western Blotting to suggest that the frequent occurrence of RNF43-G659Vfs*41 may result from error-prone replication of the 7-G repeat in MLH1-deficient tumors and that the mutation itself does not inactivate enzyme.
Fri Dec 06 00:00:00 EST 2019
Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum.
Nature microbiology
Bancells C,Llorà-Batlle O,Poran A,Nötzel C,Rovira-Graells N,Elemento O,Kafsack BFC,Cortés A
71-5500 was used in Immunocytochemistry-immunoflourescence to study the initial steps of gametocytogenesis in Plasmodium falciparum.
Tue Jan 01 00:00:00 EST 2019
Ceramides bind VDAC2 to trigger mitochondrial apoptosis.
Nature communications
Dadsena S,Bockelmann S,Mina JGM,Hassan DG,Korneev S,Razzera G,Jahn H,Niekamp P,Müller D,Schneider M,Tafesse FG,Marrink SJ,Melo MN,Holthuis JCM
71-5500 was used in Western Blotting to demonstrate the role of voltage-dependent anion channels VDAC2 as a direct effector of ceramide-mediated cell death.
Tue Apr 23 00:00:00 EDT 2019
Ceramides bind VDAC2 to trigger mitochondrial apoptosis.
Nature communications
Dadsena S,Bockelmann S,Mina JGM,Hassan DG,Korneev S,Razzera G,Jahn H,Niekamp P,Müller D,Schneider M,Tafesse FG,Marrink SJ,Melo MN,Holthuis JCM
71-5500 was used in Western Blotting to demonstrate the role of voltage-dependent anion channels VDAC2 as a direct effector of ceramide-mediated cell death.
Tue Apr 23 00:00:00 EDT 2019
Arabidopsis pollen tube germination and growth depend on the mitochondrial calcium uniporter complex.
The New phytologist
Selles B,Michaud C,Xiong TC,Leblanc O,Ingouff M
71-5500 was used in Western Blotting to show that mitochondrial Ca2+ controlled by MCUs is an additional player in Arabidopsis pollen tube germination and growth.
Sun Jul 01 00:00:00 EDT 2018
Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis.
PLoS pathogens
Zhang Z,He G,Han GS,Zhang J,Catanzaro N,Diaz A,Wu Z,Carman GM,Xie L,Wang X
71-5500 was used in Western Blotting to show that Pah1p promotes storage lipid synthesis and thus represses phospholipid synthesis which in turn restricts both viral replication and cell growth during viral infection.
Sun Apr 01 00:00:00 EDT 2018
Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis.
PLoS pathogens
Zhang Z,He G,Han GS,Zhang J,Catanzaro N,Diaz A,Wu Z,Carman GM,Xie L,Wang X
71-5500 was used in Western Blotting to show that Pah1p promotes storage lipid synthesis and thus represses phospholipid synthesis which in turn restricts both viral replication and cell growth during viral infection.
Sun Apr 01 00:00:00 EDT 2018
Hsp70 Interacts with Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 To Regulate p38MAPK Stability and Myoblast Differentiation during Skeletal Muscle Regeneration.
Molecular and cellular biology
Fan W,Gao XK,Rao XS,Shi YP,Liu XC,Wang FY,Liu YF,Cong XX,He MY,Xu SB,Shen WL,Shen Y,Yan SG,Luo Y,Low BC,Ouyang H,Bao Z,Zheng LL,Zhou YT
71-5500 was used in Western blotting to reveal a novel role of Hsp70 in regulating myoblast differentiation by interacting with MK2 to stabilize p38MAPK.
Sat Dec 15 00:00:00 EST 2018
Convergence of PASTA Kinase and Two-Component Signaling in Response to Cell Wall Stress in Enterococcus faecalis.
Journal of bacteriology
Kellogg SL,Kristich CJ
71-5500 was used in Western Blotting to probe the relationship between CroS/R and IreK, revealing convergence of IreK and the sensor kinase CroS to enhance signaling through CroS/R and increase antimicrobial resistance in E. faecalis.
Fri Jun 15 00:00:00 EDT 2018
The Misshapen kinase regulates the size and stability of the germline ring canals in the Drosophila egg chamber.
Developmental biology
Kline A,Curry T,Lewellyn L
71-5500 was used in Immunohistochemistry to suggests that Misshapen could be indirectly limiting ring canal size by altering the structure or dynamics of the actin cytoskeleton and/or adherens junctions.
Wed Aug 15 00:00:00 EDT 2018
Light Regulates the RUBylation Levels of Individual Cullin Proteins in Arabidopsis thaliana.
Plant molecular biology reporter
Christians MJ,Rottier A,Wiersma C
71-5500 was used in Western Blotting to find that light influenced the global levels of RUBylation on CULs, but not uniformly.
Thu Oct 01 00:00:00 EDT 2020
Integration of two RAB5 groups during endosomal transport in plants.
eLife
Ito E,Ebine K,Choi SW,Ichinose S,Uemura T,Nakano A,Ueda T
71-5500 was used in Western blotting to study the role of integration of RAB groups in endosomal trafficking in plants.
Fri May 11 00:00:00 EDT 2018
Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.
The Journal of biological chemistry
Park S,Cui J,Yu W,Wu L,Carmon KS,Liu QJ
71-5500 was used in Western Blotting to suggest that RSPO1-4 use distinct mechanisms in regulating Wnt and other signaling pathways, which have important implications for understanding the pleiotropic functions of RSPOs and LGRs in both normal and cancer development.
Fri Jun 22 00:00:00 EDT 2018
Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system.
eLife
Yang X,Arines FM,Zhang W,Li M
71-5500 was used in Western Blotting to provide a novel model of achieving multi-tasking for transmembrane ubiquitin ligases with interchangeable trafficking adaptors.
Mon Jan 22 00:00:00 EST 2018
PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.
The Journal of biological chemistry
Desbois M,Crawley O,Evans PR,Baker ST,Masuho I,Yasuda R,Grill B
71-5500 was used in Immunoprecipitation to demonstrate a novel role for SKP1 as an auxiliary component of the target recognition module that enhances binding of FBXO45 to NMNAT2.
Fri Sep 07 00:00:00 EDT 2018
A Rapid Induction Mechanism for Lin28a in Trophic Responses.
Molecular cell
Amen AM,Ruiz-Garzon CR,Shi J,Subramanian M,Pham DL,Meffert MK
715500 was used in western blot to identify signaling pathways that allow trophic stimuli to induce Lin28
Thu Feb 02 00:00:00 EST 2017
Gene Expression Profiling with Cre-Conditional Pseudorabies Virus Reveals a Subset of Midbrain Neurons That Participate in Reward Circuitry.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Pomeranz LE,Ekstrand MI,Latcha KN,Smith GA,Enquist LW,Friedman JM
71-5500 was used in Immunohistochemistry to identify major projections to the mesolimbic dopamine circuit from the lateral hypothalamus and dorsal raphe nucleus.
Wed Apr 12 00:00:00 EDT 2017
Suppression and synthetic-lethal genetic relationships of ΔgpsB mutations indicate that GpsB mediates protein phosphorylation and penicillin-binding protein interactions in Streptococcus pneumoniae D39.
Molecular microbiology
Rued BE,Zheng JJ,Mura A,Tsui HT,Boersma MJ,Mazny JL,Corona F,Perez AJ,Fadda D,Doubravová L,Buriánková K,Branny P,Massidda O,Winkler ME
715500 was used in immunocytochemistry and western blot to suggest that DeltadivIVA mutations are not epistatic to DeltagpsB division-protein mutations in progenitor D39 and related genetic backgrounds
Wed Mar 01 00:00:00 EST 2017
Extracellular SalB Contributes to Intrinsic Cephalosporin Resistance and Cell Envelope Integrity in Enterococcus faecalis.
Journal of bacteriology
Djorić D,Kristich CJ
71-5500 was used in Western Blotting to highlight the importance of the C-terminal SCP domain of SalB, including several conserved residues within the SCP domain, for the ability of SalB to promote cephalosporin resistance.
Fri Dec 01 00:00:00 EST 2017
ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain.
Scientific reports
Cabukusta B,Kol M,Kneller L,Hilderink A,Bickert A,Mina JG,Korneev S,Holthuis JC
715500 was used in immunocytochemistry and western blot to examine if SMSr-SAM is structurally and functionally related to the SAM domain of diacylglycerol kinase DGKd
Wed Jan 25 00:00:00 EST 2017
Dynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells.
Scientific reports
González-Jamett AM,Baez-Matus X,Olivares MJ,Hinostroza F,Guerra-Fernández MJ,Vasquez-Navarrete J,Bui MT,Guicheney P,Romero NB,Bevilacqua JA,Bitoun M,Caviedes P,Cárdenas AM
71-5500 was used in Immunohistochemistry to show actin-dependent trafficking in muscle cells is impaired upon implementing dynamin-2 mutations linked to centronuclear myopathy.
Tue Jul 04 00:00:00 EDT 2017
An unrecognized function for COPII components in recruiting the viral replication protein BMV 1a to the perinuclear ER.
Journal of cell science
Li J,Fuchs S,Zhang J,Wellford S,Schuldiner M,Wang X
715500 was used in immunocytochemistry, proximity ligation assay, and western blot to demonstrate that some coat protein complex II proteins target proteins to the perinuclear endoplasmic reticulum membrane
Sat Oct 01 00:00:00 EDT 2016
Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy.
Scientific reports
Hu Z,Wang JW,Yu D,Soon JL,de Kleijn DP,Foo R,Liao P,Colecraft HM,Soong TW
715500 was used in immunoprecipitation and western blot to propose that neonatal splice variant of CaV1.2 channels contribute to heart disease
Wed Oct 12 00:00:00 EDT 2016
Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress.
Molecular & cellular proteomics : MCP
Federspiel JD,Codreanu SG,Palubinsky AM,Winland AJ,Betanzos CM,McLaughlin B,Liebler DC
71-5500 was used in immunocytochemistry to characterize the response to electrophile stress by assembly stoichiometry and dynamics of the apoptosis signal-regulating kinase (ASK) signalosome
Wed Jun 01 00:00:00 EDT 2016
Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis.
Nature communications
Lee H,Noh H,Mun J,Gu C,Sever S,Park S
71-5500 was used in western blot describe the role of Anks1a in COPII-mediated EphA2 export from the endoplasmic reticulum
Tue Sep 13 00:00:00 EDT 2016
Glypican Is a Modulator of Netrin-Mediated Axon Guidance.
PLoS biology
Blanchette CR,Perrat PN,Thackeray A,Bénard CY
71-5500 was used in western blot to study netrin-mediated axon guidance modulated by glypican
Wed Jul 01 00:00:00 EDT 2015
Evolutionarily conserved pressure for the existence of distinct G2/M cell cycle arrest and A3H inactivation functions in HIV-1 Vif.
Cell cycle (Georgetown, Tex.)
Zhao K,Du J,Rui Y,Zheng W,Kang J,Hou J,Wang K,Zhang W,Simon VA,Yu XF
71-5500 was used in western blot to investigate how Vif from HIV recognizes substrates.
Tue Dec 15 00:00:00 EST 2015
Functional analysis of protein ubiquitination.
Analytical biochemistry
Levy-Cohen G,Blank M
71-5500 was used in western blot to discuss methods to study protein ubiquitination.
Tue Sep 01 00:00:00 EDT 2015
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation.
Cell reports
Calafate S,Buist A,Miskiewicz K,Vijayan V,Daneels G,de Strooper B,de Wit J,Verstreken P,Moechars D
71-5500 was used in western blot to test if synaptic contacts between neurons aid propagation of Tau pathology.
Tue May 26 00:00:00 EDT 2015
Hyper sensitive protein detection by Tandem-HTRF reveals Cyclin D1 dynamics in adult mouse.
Scientific reports
Zampieri A,Champagne J,Auzemery B,Fuentes I,Maurel B,Bienvenu F
71-5500 was used in immunohistochemistry - paraffin section to reveal Cyclin D1 dynamics in adult mice by hyper sensitive protein detection by tandem-HTRF
Tue Oct 27 00:00:00 EDT 2015
A transcriptional switch underlies commitment to sexual development in malaria parasites.
Nature
Kafsack BF,Rovira-Graells N,Clark TG,Bancells C,Crowley VM,Campino SG,Williams AE,Drought LG,Kwiatkowski DP,Baker DA,Cortés A,Llinás M
71-5500 was used in immunocytochemistry to investigate the mechanisms involved in parasite gametocyte formation.
Thu Mar 13 00:00:00 EDT 2014
Core binding factor beta plays a critical role by facilitating the assembly of the Vif-cullin 5 E3 ubiquitin ligase.
Journal of virology
Fribourgh JL,Nguyen HC,Wolfe LS,Dewitt DC,Zhang W,Yu XF,Rhoades E,Xiong Y
71-5500 was used in immunoprecipitation to investigate the role of core binding factor beta plays in the assembly of the Vif-cullin 5 E3 ubiquitin ligase
Sat Mar 01 00:00:00 EST 2014
Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumoniae D39.
Molecular microbiology
Tsui HT,Boersma MJ,Vella SA,Kocaoglu O,Kuru E,Peceny JK,Carlson EE,VanNieuwenhze MS,Brun YV,Shaw SL,Winkler ME
71-5500 was used in immunocytochemistry and western blot to investigate peptidoglycan synthesis using Streptococcus pneumoniae.
Wed Oct 01 00:00:00 EDT 2014
X-ray crystal structure of voltage-gated proton channel.
Nature structural & molecular biology
Takeshita K,Sakata S,Yamashita E,Fujiwara Y,Kawanabe A,Kurokawa T,Okochi Y,Matsuda M,Narita H,Okamura Y,Nakagawa A
71-5500 was used in western blot to report a crystal structure for mouse Hv in the resting state at 3.45-Å resolution.
Tue Apr 01 00:00:00 EDT 2014
Inhibition of mediodorsal thalamus disrupts thalamofrontal connectivity and cognition.
Neuron
Parnaudeau S,O'Neill PK,Bolkan SS,Ward RD,Abbas AI,Roth BL,Balsam PD,Gordon JA,Kellendonk C
71-5500 was used in immunocytochemistry to modulate the levels of mediodorsal thalamus activity and assess cognitive behaviors.
Wed Mar 20 00:00:00 EDT 2013
Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination.
The EMBO journal
Tikoo S,Madhavan V,Hussain M,Miller ES,Arora P,Zlatanou A,Modi P,Townsend K,Stewart GS,Sengupta S
71-5500 was used in immunocytochemistry and western blot to study the mechanism through which the Bloom syndrome helicase suppresses homologous recombination at sites of DNA damage
Wed Jun 12 00:00:00 EDT 2013
Differential requirements for HIV-1 Vif-mediated APOBEC3G degradation and RUNX1-mediated transcription by core binding factor beta.
Journal of virology
Du J,Zhao K,Rui Y,Li P,Zhou X,Zhang W,Yu XF
71-5500 was used in western blot to elucidate the function of different Vif domains.
Fri Feb 01 00:00:00 EST 2013
Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39.
Molecular microbiology
Land AD,Tsui HC,Kocaoglu O,Vella SA,Shaw SL,Keen SK,Sham LT,Carlson EE,Winkler ME
71-5500 was used in Western Blotting to suggest that GpsB and Pbp2x mediate septal ring closure in Streptococcus pneumoniae D39.
Sun Dec 01 00:00:00 EST 2013
The RNA-binding protein repertoire of embryonic stem cells.
Nature structural & molecular biology
Kwon SC,Yi H,Eichelbaum K,Föhr S,Fischer B,You KT,Castello A,Krijgsveld J,Hentze MW,Kim VN
71-5500 was used in western blot to identify the RNA binding proteins in embryonic stem cells.
Sun Sep 01 00:00:00 EDT 2013
Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase.
Nature communications
Zhu C,Gao W,Zhao K,Qin X,Zhang Y,Peng X,Zhang L,Dong Y,Zhang W,Li P,Wei W,Gong Y,Yu XF
71-5500 was used in western blot to investigate the mechanism of SAMHD's dGTP-activated dNTPase function.
Tue Jul 15 00:00:00 EDT 2014
Inducible coexpression of connexin37 or connexin40 with connexin43 selectively affects intercellular molecular transfer.
The Journal of membrane biology
Gemel J,Nelson TK,Burt JM,Beyer EC
71-5500 was used in western blot to examine the effects of coexpressing Cx40 or Cx37 with Cx43 at different ratios.
Fri Jun 01 00:00:00 EDT 2012
The oligomeric state sets GABA(B) receptor signalling efficacy.
The EMBO journal
Comps-Agrar L,Kniazeff J,Nørskov-Lauritsen L,Maurel D,Gassmann M,Gregor N,Prézeau L,Bettler B,Durroux T,Trinquet E,Pin JP
71-5500 was used in western blot to study GABA(B) receptor complexes in the brain using FRET.
Fri May 06 00:00:00 EDT 2011
Amyloid precursor-like protein 2 cleavage contributes to neuronal intranuclear inclusions and cytotoxicity in spinocerebellar ataxia-7 (SCA7).
Neurobiology of disease
Takahashi-Fujigasaki J,Breidert T,Fujigasaki H,Duyckaerts C,Camonis JH,Brice A,Lebre AS
71-5500 was used in western blot to identify amyloid precursor-like protein 2 as a partner protein for ataxin-7
Sat Jan 01 00:00:00 EST 2011
Different domains are critical for oligomerization compatibility of different connexins.
The Biochemical journal
Martínez AD,Maripillán J,Acuña R,Minogue PJ,Berthoud VM,Beyer EC
71-5500 was used in Immunohistochemistry-immunofluorescence to suggest that amino acids in the third transmembrane domain are critical for oligomerization with Cx43 and Cx45.
Sun May 15 00:00:00 EDT 2011
Genetic and biochemical analysis of high iron toxicity in yeast: iron toxicity is due to the accumulation of cytosolic iron and occurs under both aerobic and anaerobic conditions.
The Journal of biological chemistry
Lin H,Li L,Jia X,Ward DM,Kaplan J
Fri Feb 04 00:00:00 EST 2011
Sumoylation regulates nuclear localization of repressor DREAM.
Biochimica et biophysica acta
Palczewska M,Casafont I,Ghimire K,Rojas AM,Valencia A,Lafarga M,Mellström B,Naranjo JR
71-5500 was used in immunoprecipitation to report that sumoylation regulates the nuclear localization of DREAM in differentiated neurons
Sun May 01 00:00:00 EDT 2011
Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors.
The Journal of biological chemistry
Goh WI,Sudhaharan T,Lim KB,Sem KP,Lau CL,Ahmed S
71-5500 was used in immunocytochemistry to investigate Rif-induced filopodia.
Fri Apr 15 00:00:00 EDT 2011
11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Holmes MC,Carter RN,Noble J,Chitnis S,Dutia A,Paterson JM,Mullins JJ,Seckl JR,Yau JL
71-5500 was used in immunohistochemistry - frozen section to test if 11beta-HSD1 contributes to cognitive deficits associated with aging male mice
Wed May 19 00:00:00 EDT 2010
Internalization of coxsackievirus A9 is mediated by {beta}2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin.
Journal of virology
Heikkilä O,Susi P,Tevaluoto T,Härmä H,Marjomäki V,Hyypiä T,Kiljunen S
71-5500 was used in immunocytochemistry to study internalization of CAV9 into human lung carcinoma cells
Thu Apr 01 00:00:00 EDT 2010
Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization.
American journal of physiology. Cell physiology
Schalper KA,Sánchez HA,Lee SC,Altenberg GA,Nathanson MH,Sáez JC
Wed Dec 01 00:00:00 EST 2010
Silencing of an abdominal Hox gene during early development is correlated with limb development in a crustacean trunk.
Evolution & development
Hsia CC,Paré AC,Hannon M,Ronshaugen M,McGinnis W
71-5500 was used in immunohistochemistry to test if Artemia abd-A represses limbs in Drosophila embryos
Thu Aug 12 00:00:00 EDT 2010
Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration.
The EMBO journal
Rives ML,Vol C,Fukazawa Y,Tinel N,Trinquet E,Ayoub MA,Shigemoto R,Pin JP,Prézeau L
71-5500 was used in immunoprecipitation to study GABA(B) receptor-mediated potentiation of mGlu receptor signaling in Purkinje neurons
Wed Aug 05 00:00:00 EDT 2009
Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.
Proceedings of the National Academy of Sciences of the United States of America
Geng L,Boehmerle W,Maeda Y,Okuhara DY,Tian X,Yu Z,Choe CU,Anyatonwu GI,Ehrlich BE,Somlo S
71-5500 was used in immunocytochemistry to elucidate the physiological role of the PC2/Stx5 complex
Tue Oct 14 00:00:00 EDT 2008
Connexin hemichannel composition determines the FGF-1-induced membrane permeability and free [Ca2+]i responses.
Molecular biology of the cell
Schalper KA,Palacios-Prado N,Retamal MA,Shoji KF,Martínez AD,Sáez JC
71-5500 was used in western blot to examine the contributions of connexins on FGF-1-induced cellular responses
Fri Aug 01 00:00:00 EDT 2008
JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes.
Nature
Frescas D,Guardavaccaro D,Bassermann F,Koyama-Nasu R,Pagano M
71-5500 was used in immunoprecipitation to characterize human JHDM1B.
Thu Nov 08 00:00:00 EST 2007
Polarized trafficking of the aquaporin-3 water channel is mediated by an NH2-terminal sorting signal.
American journal of physiology. Cell physiology
Rai T,Sasaki S,Uchida S
Sun Jan 01 00:00:00 EST 2006
p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
Molecular and cellular biology
Leaner VD,Donninger H,Ellis CA,Clark GJ,Birrer MJ
71-5500 was used in ChIP assay to identify Ras-GRF1 as a c-Jun/AP-1-regulated gene that is essential for anchorage-independent growth of immortalized rat fibroblasts
Fri Apr 01 00:00:00 EST 2005
Connexin43 with a cytoplasmic loop deletion inhibits the function of several connexins.
Biochemical and biophysical research communications
Wang M,Martínez AD,Berthoud VM,Seul KH,Gemel J,Valiunas V,Kumari S,Brink PR,Beyer EC
71-5500 was used in immunocytochemistry and western blot to determine role of amino acids within the cytoplasmic loop of connexins
Fri Aug 12 00:00:00 EDT 2005
Connexin43 and connexin26 form gap junctions, but not heteromeric channels in co-expressing cells.
Journal of cell science
Gemel J,Valiunas V,Brink PR,Beyer EC
Sat May 15 00:00:00 EDT 2004
p51/p63 Controls subunit alpha3 of the major epidermis integrin anchoring the stem cells to the niche.
The Journal of biological chemistry
Kurata S,Okuyama T,Osada M,Watanabe T,Tomimori Y,Sato S,Iwai A,Tsuji T,Ikawa Y,Katoh I
71-5500 was used in ChIP assay and western blot to determine the role of ITGA3 encoding integrin alpha(3) in skin development
Fri Nov 26 00:00:00 EST 2004
Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.
The Journal of biological chemistry
Cai Y,Anyatonwu G,Okuhara D,Lee KB,Yu Z,Onoe T,Mei CL,Qian Q,Geng L,Wiztgall R,Ehrlich BE,Somlo S
71-5500 was used in immunoprecipitation and western blot to study the effect of phosphorylation on polycystin-2 function
Fri May 07 00:00:00 EDT 2004
A carboxyl terminal domain of connexin43 is critical for gap junction plaque formation but not for homo- or hetero-oligomerization.
Cell communication & adhesion
Martínez AD,Hayrapetyan V,Moreno AP,Beyer EC
71-5500 was used in immunocytochemistry to investigate the biosynthesis and oligomerization of Cx43.
Mon Nov 15 00:00:00 EST 2004
Sp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells.
The Journal of biological chemistry
Won J,Yim J,Kim TK
71-5500 was used in immunoprecipitation to describe the systematic analyses of hTERT promoter to understand the transcriptional repression mechanism of the hTERT gene in normal human somatic cells.
Fri Oct 11 00:00:00 EDT 2002
In vivo requirement of the alpha-syntrophin PDZ domain for the sarcolemmal localization of nNOS and aquaporin-4.
The Journal of cell biology
Adams ME,Mueller HA,Froehner SC
Mon Oct 01 00:00:00 EDT 2001
In vivo requirement of the alpha-syntrophin PDZ domain for the sarcolemmal localization of nNOS and aquaporin-4.
The Journal of cell biology
Adams ME,Mueller HA,Froehner SC
Mon Oct 01 00:00:00 EDT 2001
Characterization of multiple isoforms of protein 4.1R expressed during erythroid terminal differentiation.
Blood
Gascard P,Lee G,Coulombel L,Auffray I,Lum M,Parra M,Conboy JG,Mohandas N,Chasis JA
Tue Dec 01 00:00:00 EST 1998