This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human HAGH.
The enzyme encoded by the HAGH gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene. Diseases associated with HAGH include Hydroxyacyl Glutathione Hydrolase Deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Glx II; Glyoxalase II; Hydroxyacylglutathione hydrolase, mitochondrial; hydroxyacylglutathione hydroxylase
Gene Aliases: GLO2; GLX2; GLXII; HAGH; HAGH1
UniProt ID: (Human) Q16775
Entrez Gene ID: (Human) 3029
Molecular Function: hydrolase