Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
HAPLN1 belongs to the HAPLN family and contains 1 Ig like V type (immunoglobulin like) domain and 2 Link domains. HAPLN1 stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix. Diseases associated with HAPLN1 include Cerebral Creatine Deficiency Syndrome 3 and Rheumatoid Arthritis, Systemic Juvenile.
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Protein Aliases: Cartilage link protein; cartilage link protein 1; cartilage linking protein 1; Cartilage-link protein; Cartilage-linking protein 1; Hyaluronan and proteoglycan link protein 1; hyaluronan proteoglycan link protein 1; link protein; LP; Proteoglycan link protein
Gene Aliases: BB099155; CLP; CRT1; CRTL1; Crtl1l; fc26f11; fc37g04; fc50e12; fc55h01; HAPLN1; LP; LP-1; wu:fc26f11; wu:fc37g04; wu:fc50e12; wu:fc55h01