|Western Blot (WB)||1:5000|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Rat / IgG1|
|Immunogen||Synthetic peptide corresponding to residues T(640) L L A R S A R R S A G S P A S P L V P V R A G P L L A R G P W A S T S(675) of rat HCN3.|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA3-902 detects HCN3 from human, mouse and rat samples.
MA3-902 has been successfully used in Western blotting and immunohistochemistry procedures. By Western blot MA3-902 detects a ~90 KDa band representing HCN3.
The MA3-902 immunogen is a synthetic peptide corresponding to residues T(640) L L A R S A R R S A G S P A S P L V P V R A G P L L A R G P W A S T S(675) of rat HCN3.
MA3-902 (clone TLL6C5) is a rat monoclonal hybridoma, produced by immunizing a rat, isolating the spleen cells, creating the hybridoma and successively injecting these cells into a mouse to produce ascites.
HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. HCN3 has been detected in the brain, but with less expression than other HCN channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HAC-3; hyperpolarization activated cyclic nucleotide-gated potassium channel 3; Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel-3; Hyperpolarization-activated cation channel 3; hyperpolarization-activated, cyclic nucleotide-gated K+ 4; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3; Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel-
Gene Aliases: BCNG-4; Bcng4; Hac3; HCN3; Hcn4; KIAA1535
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