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Product Details
75-175-FL594
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N141/28
Immunogen
Fusion protein amino acids 660-779 (cytoplasmic C-terminus) of mouse HCN3 (accession number O88705) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
594/615 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. HCN3 has been detected in the brain, but with less expression than other HCN channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HAC-3; Hyperpolarization-activated cation channel 3; hyperpolarization-activated, cyclic nucleotide-gated K+ 4; MGC131493; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
Gene Aliases: BCNG-4; Bcng4; Hac3; Hcn3; Hcn4
UniProt ID: (Mouse) O88705, (Rat) Q9JKA8
Entrez Gene ID: (Mouse) 15168, (Rat) 114245
nucleotide binding
ion channel activity
intracellular cAMP activated cation channel activity
voltage-gated ion channel activity
voltage-gated sodium channel activity
voltage-gated potassium channel activity
potassium channel activity
sodium channel activity
protein binding
cAMP binding
ion channel
transporter
transport
ion transport
potassium ion transport
sodium ion transport
regulation of ion transmembrane transport
sodium ion transmembrane transport
regulation of membrane potential
transmembrane transport
potassium ion transmembrane transport
cellular response to cAMP
response to cisplatin
cellular response to dopamine
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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